In vitro anti-inflammatory activity and tissue culture studies on Tinospora cordifolia
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2016, Vol 2, Issue 10
Abstract
The present study deals with the in vitro anti-inflammatory in methanolic extracts of in vivo (leaf and stem) and in vitro (callus) plant parts of Tinospora cordifolia (Acanthaceae) is a medicinal plant of immense therapeutic value.The present work is based on developing a protocol for the callus induction in T. cordifolia from stem and leaf explants. The highest rate of callus (70.82%) was observed on MS medium fortified with 1.5 mg/L 2, 4-D and 0.3 mg/L BAP. The methanolic extracts of all plant parts exhibited remarkable anti-inflammatory activity action. The maximum amount of membrane stabilization was found in stem callus (78.15% at a dose of 100μg/ml) as compare to other plant and callus parts tested. Therefore, our studies support the isolation and the use of active constituents from in vivo and in vitro plant parts of T. cordifolia in treating inflammations.
Authors and Affiliations
Maanhvizhi. E1 and Revathi. K2*
Correlation of hepatocellular carcinoma with Hepatitis virus C, HBsAg and alcohol.
Alcohol intake has been definitely recognized as a cause of chronic liver diseases, including hepatocellular carcinoma (HCC) (1, 2). Alcohol could be involved in the development of HCC through both direct (genotoxic) and...
Biochemical Investigations vs Ultrasonography in Diagnosis of Bile Stones
Gallbladder stones are an extremely common disorder and are usually asymptomatic. Some patients experience biliary colic, an intermittent and often severe pain in the epigastrium or right upper quadrant, and at times bet...
An update on hypoxic regulation of iron homeostasis and bone marrow environment
Iron is very important in the body especially for effective erythropoiesis and should be maintained at a normal level. Some disease conditions may precipitate increased or decreased levels of iron. The body has some iron...
Relationship between Helicobacter pylori infection and spontaneous abortion: A Systematic Review and meta-analysis
Introduction: Abortion is one of the most common complications of pregnancy. Infection is one of the main causes of abortion, a cause which is more important in spontaneous abortion; infections account for only 5% of rec...
In-vitro cytotoxicity and Phytochemical Activity in Bryophyllum pinnatum
BACKGROUND: Plants and plant-based medicaments are the basis of many of the modern pharmaceuticals used for our various ailments ). Progress over the centuries towards a better understanding of a plant derived medicine h...