In-Vitro Antibacterial Effect of Crude Extract of Chromolaena Odorata Leaves on Wound Isolates
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
Medicinal plants have played an important role in prevention and control of diseases. The abundance of plants on the earth’s surfaces has led to an increasing interest in the investigation of different extracts obtained from traditional plant as potential sources of new antimicrobial agents. This study was carried out to determine the antibacterial effect of the crude extract of Chromolaena odorata leaves on some wound isolates (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella species). The result shows that the crude extract of Chromolaena odorata leaves was effective on the isolated bacteria, however the control drug Ciprofloxacin had greater inhibition on the tested organism than the plant extracts. The zone of inhibition of crude extract of Chromolaena odorata leaves on S. aureus ranged from 7mm - 18mm, Klebsiella species ranged from 6mm - 17mm, Pseudomonas aeruginosa 5mm -15mm and Escherichia coli 5mm-13mm while the control drug (ciprofloxacin) ranged from16mm-20mm. The minimum inhibitory concentration ranged from (25.0% to 50.0%).This research work establishes a good support to the use of this plant in herbal remedies and as base for development of new drugs against wound isolates.
Authors and Affiliations
Nwachukwu, Ifeanyi, Aliga, Chinanu; 3, Upabi, Chibueze F, Ukogo, Ifeoma
Keywords
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- EP ID EP386757
- DOI 10.9790/3008-1106024952
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