In-vitro antioxidant activity of crataeva magna lour. dc bark extract
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2012, Vol 2, Issue 0
Abstract
The plant Crataeva magna belonging to family Capparaceae is used in anti spasmodic, hypotensive, anti-inflammatory, hypoglycemic, anti protozoal, analgesic purposes. The present study was carried out to evaluate appropriate animal model. The antioxidative potential of different solvent extracts of Crataeva magna were evaluated using 1,1-Diphenyl-2-Picrylhydrazyl (DPPH), 2,2 ’-Azino-Bis(3-ethylbenzthiazoline-6-Sulphonic acid) (ABTS), superoxide radical, hydroxyl radical, nitric oxide radical scavenging activities and lipid peroxidation inhibition assay. Among those solvent extracts, ethanolic extract of C. magna exhibited highest level of antioxidant activities. The ethanolic extract also inhibited H 2O2 mediated haemolysis and lipid peroxidation in human RBC.
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