In-Vitro antioxidant potential and phytochemical screening of Tectona grandis Linn. leaves

Abstract

Tectona grandis Linn. belongs to family Verbenaceae commonly known as Teak and is found in India and South-East Asian countries. It is known for its medicinal value traditionally to cure diseases such as diabetes, anti-inflammatory and infectious diseases and has its timber value too. In-vitro antioxidant activity and phytochemical investigation was carried out for successive solvent extracts such as petroleum ether, chloroform, ethyl acetate, methanol and water. The reducing power assay and nitric oxide inhibition assay and DPPH assay demonstrate that the methanolic extract have higher antioxidant activity than others when compared with ascorbic acid as standard. The Phytochemical investigation of methanolic extract also reveals that it has tannins, flavonoids and phenolic contents present in it which are responsible for its antioxidant activity. Thus methanolic extract of the plant will be suggested for futher investigation to determine in-vivo antioxidant activity for diseases in which oxidative stress play a major role.

Authors and Affiliations

A. S. Kushwah, Parminder Kaur, Ramandeep Singh

Keywords

Related Articles

Synthesis, Characterization and Anticonvulsant Activity on Novel Thiourea Derivatives

The present research work involves the synthesis of a series of N-Substituted Thiourea derivatives (T1- T3) by refluxing 8-(3-nitrophenoxy) octan-1-amine in THF (Tetrahydrofuran). The synthesized compounds were charact...

Importance of Agni and its Impact on Human Body

Ayurveda is the ancient Indian system of life sciences and Medicine, its historicity going back to the Vedas. Its classical knowledge and practice is based on its own physics and biology, its unique pronature holistic...

Development of Lacidipine loaded nanostructured lipid carriers (NLCs) for bioavailability enhancement

Nanostructured Lipid Carriers (NLCs) are new generation Nanoparticle system, which have shown a lot of advantages over conventional Solid lipid nanoparticles, such as improved drug incorporation and release properties....

Pioneering and Encouraging Approach Mucoadhesive Drug Delivery System

A Propitious Novel Drug delivery method, Mucoadhesive drug delivery system considerably increase dosage form residence time, furthermore augmenting the affinity with the tissue and localizing the drug in a specific regio...

In-Vitro Cytotoxicity Study of Some Indigenous Medicinal Plants on Vero Cell Line

The ethno botany and ubiquitous plants as a source of medicine has been an important component of the health care system providing a rich resource for natural drug research and development. Natural products from medici...

Download PDF file
  • EP ID EP31449
  • DOI -
  • Views 447
  • Downloads 2

How To Cite

A. S. Kushwah, Parminder Kaur, Ramandeep Singh (2013). In-Vitro antioxidant potential and phytochemical screening of Tectona grandis Linn. leaves. International Journal of Pharmaceutical and Medicinal Reserach, 1(1), -. https://europub.co.uk/articles/-A-31449