In Vitro Cytotoxicity and Glucose Uptake Activity of Gymnemic Acid Fraction of Gymnema Sylvestre Leaves
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2016, Vol 4, Issue 2
Abstract
Gymnema sylvestre is a native plant of India belonging to the family Asclepedaceae. The aim of the present study is to evaluate the cytotoxicity and glucose uptake activity of gymnemic acid fraction of gymnema sylvestre using L-6 cell lines. The results showed that the gymnemic acid fraction of gymnema sylvestre leaves did not confer any cytotoxicity and showed better glucose uptake potential. The results were compared with metformin, which were used as the standard type 2 antidiabetic drug. Metformin (100 μg/ml) enhance the glucose uptake over control.
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