In Vitro Cytotoxicity and Glucose Uptake Activity of Gymnemic Acid Fraction of Gymnema Sylvestre Leaves
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2016, Vol 4, Issue 2
Abstract
Gymnema sylvestre is a native plant of India belonging to the family Asclepedaceae. The aim of the present study is to evaluate the cytotoxicity and glucose uptake activity of gymnemic acid fraction of gymnema sylvestre using L-6 cell lines. The results showed that the gymnemic acid fraction of gymnema sylvestre leaves did not confer any cytotoxicity and showed better glucose uptake potential. The results were compared with metformin, which were used as the standard type 2 antidiabetic drug. Metformin (100 μg/ml) enhance the glucose uptake over control.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP325634
- DOI -
- Views 94
- Downloads 0
Prevalence of GDM diagnosed by DIPSI Guidelines
Background: the prevalence of diabetes mellitus is increasing worldwide and more in developing countries including India. The increasing prevalence in developing countries is related to increasing urbanization, decreasin...
Studies on Pharmacological Screening of Some Medicinal Plants for their Antimicrobial and Feed Additives
Antibiotics such as avoparcin, bacitracin, lincomycin, penicillin-G -procaine, chlortetracycline and virginiamycin promote growth because of an effect on the microflorain the gastrointestinal tract. Throughout the world,...
A Study to Focus on Risk Assessment of Various Cardiovascular Diseases by Using Framingham Heart Study
Background: Cardiovascular diseases (CVD) account for nearly one third of all deaths worldwide. The available rehabilitation and preventive measures include life style modification, treatment with drug and intervention p...
Treatment Modalities in Irritable Bowel Syndrome in a Tertiary Hospital in North India
Background: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, affecting 4 to 26% population worldwide. Multiple risk factors are associated in pathophysiology of IBS; accordingly its therap...
First Trimester Prediction of Hypertensive Disorders in Pregnancy Using Doppler Ultrasonography in an African Population
Objective: To determine the predictive value of abnormal Doppler indices in the first trimester for development of hypertensive disorders in pregnancy in an African population. Methods:This was a longitudinal study in Il...