In Vitro Evaluation of Combined Dosage of ApiumgraveolensDulce and BryophyllumpinnatumKurz for Antigout Activity
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 4
Abstract
Abstract: The present study aimed at theIn VitroEvaluation of Xanthine Oxidase Inhibitory Activity of Apiumgraveolensdulce and Bryophyllumpinnatumkurz. The activity was performed usingethanolic extract of leaves and stalk of Apiumgraveolensdulce and fresh juice of leaves of Bryophyllumpinnatumkurz at various concentrations (100µg, 200µg, 300µg, 400µg, 500µg, 600µg, 700 µg, 800µg). In this study Allopurinol was used as a standard drug. The results were noted in terms of highest percentage inhibition of Xanthine oxidase. The combination of ethanolic extract of leaves and stalk of Apiumgraveolensdulce and fresh juiceof leaves of Bryophyllumpinnatumkurz shows significant effect at highest concentration such as 800µg in combination group. Keywords: Allopurinol, Apiumgraveolensdulce, Bryophyllumpinnatumkurz, Potassium oxonate.
Authors and Affiliations
RhemaNiteen Dongre
Keywords
Related Articles
- EP ID EP397441
- DOI -
- Views 69
- Downloads 0
A Rapid Derivative Spectrophotometric Method for Simultaneous Determination of Ethinylestradiol and Drospirenone in Dosage Forms
Abstract:A combination of ethinylestradiol and drospirenone is used as an oral contraceptive and also for the treatment of premenstrual dysphoric disorders, acne and hirsutism. In this study, a derivative spectrophotomet...
Application of QbD Approach to Development and Validation of a Novel UV- Spectrophotometric Method for Quantitative Estimation of Quetiapine Fumarate in Bulk and Pharmaceutical Formulation (Tablets)
Abstract:Stability Indicating UV-spectrophotometric analytical method validation for the estimation of Quetiapine fumarate have already been reported, but no studies reported so far include the application of Analytical...
Development and Validation of Stability Indicating Rp-Hplc Method for the Simultaneous Estimation of Sofosbuvir and DaclatasvirDihydrochloride in Bulk Drug and Pharmaceutical Dosage Form
Abstract:A new stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Sofosbuvir and Daclatasvir in pharmaceutical dosage form and bulk drug. The optimized conditions for the s...
A Case of Minocycline Induced Buccal Mucosa Hyper pigmentation
Abstract: We present a patient exposed to minocycline for 3 years for treatment of resacea, presenting with disfiguring buccal mucosa hyper pigmentation. Discontinuation of the minocycline resulted in dramatic improvemen...
The Ultrasound-Guided Biopsy in Breast Cancer
Abstract:Ultrasonography is a widely used imaging technique that has many clinical applications. The early staging of the metastatic carcinoma is one of these widely uses. FNA and core biopsies have exceedingly replaced...