In-vitro susceptibility of methicillin-resistant Staphylococcus aureus strains to antibiotics
Journal Title: Dicle Tıp Dergisi - Year 2011, Vol 38, Issue 4
Abstract
Objectives: Methicillin resistance of S.aureus strains sourced from hospitals and community-acquired has been increasing. The aim of this cross-sectional study is to determine the resistance rates to alternative antibiotics of meticilline resistant S.aureus (MRSA) strains, where the multiple resistances are encountered the most. Materials and methods: A total of 100 MRSA strains isolated consequently from the clinical samples of hospitalized patients in Erciyes University Medical Faculty Hospitals between September 2008 and October 2009 were included in the study. According to “Clinical and Laboratory Standards Institude (CLSI)” criteria, antimicrobial susceptibility testing was performed by Kirby-Bauer disk diffusion method. Results: The rates of resistance to antibiotics of the MRSA strains included within the study were 77% to erythromycin, 1% to trimethoprim/sulfamethoxazole (TMP-SXT), 90% to rifampin, 63% clindamycin, 84% to gentamicin and 0% to teicoplanin and vancomycin. Conclusion: All MRSA strains were susceptible to vancomycine and teicoplanin. On the other hand, TMP-SXT seems to be alternative agent for treatment of MRSA infections.
Authors and Affiliations
İsmail Güler, Hüseyin Kılıç, M. Altay Atalay, Duygu Perçin, Barış Erçal
Keywords
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