Incidence and clinical importance of prostate cancer in patients who underwent radical cystoprostatectomy
Journal Title: Ege Tıp Dergisi - Year 2015, Vol 54, Issue 2
Abstract
Aim: Incidental prostate adenocarcinomas which are detected in radical cystoprostatectomy (RCP) specimens are generally localized, well differentiated and have no clinical importance. In this study, we aimed to determine the rate of incidental prostate adenocarcinoma in patients underwent RCP and assess its effect on survival of the patients. Materials and Methods: The patients who underwent RCP for urothelial bladder cancer between September 2007 and March 2014 were analyzed retrospectively. Deep muscle invasion of urothelial carcinoma or high grade transitional epithelial cell carcinoma that could not be controlled by transurethral resection were the indications for surgery. Standard RCP and bilaterally expanded pelvic lymphadenectomy were performed in all patients. All samples of the cystoprostatectomy specimen were examined; Gleason degree of tumor, concurrent prostatic intraepithelial neoplasia, extracapsular extension, invasion of seminal vesicle, and metastasis of lymph nodes were evaluated. Results: Incidental prostate adenocarcinoma was diagnosed in 26 of 126 patients (20.6%) who underwent RCP for bladder urothelial carcinoma. The stages of prostate cancer were pT2a in 16 patients (61.5%), pT2c in 8 patients (30.7%), and T3b in 2 patients (7.6%). Gleason score was detected as lower than 6 in 18 patients, 7 (4+3) in 6 patients, and 9 (5+4) in 2 patients. Conclusion: All prostate tissue should be resected with no residual prostate tissue left in patients who underwent RCP for bladder cancer. The high coincidence of bladder and prostate cancers should be kept in mind, careful and detailed pathological examinations are needed.
Authors and Affiliations
Hakan Türk, Mustafa KARABIÇAK, Sıtkı Ün, Hüseyin Tarhan, Okan Nabi Yalbuzdağ, Ümit BAYOL, Tufan Süelözgen, Cemal Selçuk İşoğlu, Ferruh Zorlu
Keywords
Related Articles
- EP ID EP341997
- DOI 10.19161/etd.344113
- Views 89
- Downloads 0
Evaluation of 'anti-HBc only' serological pattern detected in patients admitted to Ege University Hospital
Aim: The aim of the study is to determine the prevalance of serological pattern 'anti-HBc alone' in samples of patients sent to Ege University Virology Laboratory for the determination of hepatitis B markers and to deter...
Correlation of mid-trimester homocysteine, vitamin B12 and folate levels with adverse pregnancy outcomes: A clinical study
Aim: The aim of this study is to determine if maternal serum levels of folate, vitamin B12 and homocysteine at 20-26 weeks of gestation are associated with subsequent adverse pregnancy outcomes. Materials and Methods: Th...
Partial anomalous pulmonary venous return with intact atrial septum: A rare congenital anomaly
Partial anomalous pulmonary venous return with intact atrial septum anomaly is usually asymtomatic in pediatric population. Diagnose of this anomaly can be challenging with our routine eveluation methods like ECG, teleca...
Cosmetic aspects in minimally invasive parathyroidectomy: Is minimally invasive approach superior?
Aim: The aim of this study was to determine whether minimally invasive parathyroid surgery has any positive impact on cosmesis. Materials and Methods: This case control study included 28 parathyroidectomized patients, wh...
İmmun checkpoint inhibitörleri ilişkili bağ dokusu hastalıkları
İmmün checkpoint inhibitörleri kanser tedavisinde kullanılan ve kullanımı gün geçtikçe artan ilaçlardır. Bu ilaçlarla hemen her organa ait immün ilişkili yan etkiler bildirilmiştir. Hepatit, kolit, pnömoni, döküntü, tiro...