Incidence and clinical importance of prostate cancer in patients who underwent radical cystoprostatectomy
Journal Title: Ege Tıp Dergisi - Year 2015, Vol 54, Issue 2
Abstract
Aim: Incidental prostate adenocarcinomas which are detected in radical cystoprostatectomy (RCP) specimens are generally localized, well differentiated and have no clinical importance. In this study, we aimed to determine the rate of incidental prostate adenocarcinoma in patients underwent RCP and assess its effect on survival of the patients. Materials and Methods: The patients who underwent RCP for urothelial bladder cancer between September 2007 and March 2014 were analyzed retrospectively. Deep muscle invasion of urothelial carcinoma or high grade transitional epithelial cell carcinoma that could not be controlled by transurethral resection were the indications for surgery. Standard RCP and bilaterally expanded pelvic lymphadenectomy were performed in all patients. All samples of the cystoprostatectomy specimen were examined; Gleason degree of tumor, concurrent prostatic intraepithelial neoplasia, extracapsular extension, invasion of seminal vesicle, and metastasis of lymph nodes were evaluated. Results: Incidental prostate adenocarcinoma was diagnosed in 26 of 126 patients (20.6%) who underwent RCP for bladder urothelial carcinoma. The stages of prostate cancer were pT2a in 16 patients (61.5%), pT2c in 8 patients (30.7%), and T3b in 2 patients (7.6%). Gleason score was detected as lower than 6 in 18 patients, 7 (4+3) in 6 patients, and 9 (5+4) in 2 patients. Conclusion: All prostate tissue should be resected with no residual prostate tissue left in patients who underwent RCP for bladder cancer. The high coincidence of bladder and prostate cancers should be kept in mind, careful and detailed pathological examinations are needed.
Authors and Affiliations
Hakan Türk, Mustafa KARABIÇAK, Sıtkı Ün, Hüseyin Tarhan, Okan Nabi Yalbuzdağ, Ümit BAYOL, Tufan Süelözgen, Cemal Selçuk İşoğlu, Ferruh Zorlu
Keywords
Related Articles
- EP ID EP341997
- DOI 10.19161/etd.344113
- Views 122
- Downloads 0
Splenik arter psödoanevrizmasında acil endovasküler tedavi
Amaç: Splenik arter psödoanevrimaları (SAPA) nadir görülen ancak rüptüre olduğunda yüksek mortalite oranı olan akut batın nedenlerindendir. Travma sonrası splenik arterde yaralanma ve aktif kanamanın olması da mortalites...
Biyolojik ajanların pulmoner komplikasyonları
İnflamatuvar romatolojik hastalıklarda biyolojik ajanların kullanımı ile ilgili veri sayısı artmaktadır. Son zamanlarda, biyolojik ajanlarla ilişkili non-enfeksiyöz komplikasyonlar arasında en sık granülomatöz hastalık v...
Clinical and demographic characteristics of patients with lower limb amputation
Aim: Lower limb loss affects an individual’s ability to stand, transfer, and ambulate. The aim of this study is to assess clinical and demographic characteristics of patients with lower limb amputation. Materials and Met...
Anti-TNF tedavi seyrinde gelişen otoimmün hastalıklar: Eşlik eden hastalık mı? İlaca mı bağlı?
Anti-TNF tedavilerin romatolojik ve otoimmün hastalıkların tedavisinde yaygın kullanımı ve uzun dönem takipleri ile birlikte, paradoksal olarak anti-TNF ilişkili otoimmün hastalıklarla ilgili artan sayıda bildiriler olma...
Prospective-observational evaluation of the 50 meningomyelocele neonates
Aim: We aimed to analyze the clinical outcomes and maternal sociodemographic features of the patients followed in the neonatal intensive care unit with meningomyelocele diagnosis. Materials and Methods: Babies with meni...