Inclusion of Human Chorionic Gonadotropin in the Family of Therapeutic Glycoproteins
Journal Title: Women's Health – Open Journal - Year 2017, Vol 3, Issue 1
Abstract
The family of therapeutic glycoproteins contains many members. Some of them have become valuable therapeutic agents in saving the countless number of human lives from some of the most dreadful diseases. They are increasingly taking a center stage among biotherapeutics. The technologies of glycoengineering are making a further impact by modifying the glycan moieties, which make them biologically more active and increase their effectiveness and pharmacokinetics, etc. Human Chorionic Gonadotropin (hCG) has been used in reproductive medicine for the last several decades. The paradigm shift on the hCG actions has created additional therapeutic opportunities against many menacing and dangerous diseases that are no less important than the ones treated by some of the prominent members of the therapeutic glycoproteins family. However, to the best of the authors’ knowledge, hCG has never been included in this family or tapped the potential of glycoengineering to make hCG even more therapeutically effective than the currently used preparations. It is time to include hCG in the family and begin glycoengineering on recombinant hormone.
Authors and Affiliations
C. V. Rao
Keywords
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- EP ID EP554903
- DOI 10.17140/WHOJ-3-119
- Views 142
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