Increased prevalence of MDR non fermenters group of bacteria recovered from nosocomial infections in tertiary care hospital, East Midnapur, West Bengal
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 9, Issue 3
Abstract
Aim of study: To evaluate the incidence rate of Non-fermenters group of bacteria along with their multidrug resistant pattern. Materials and methods: A retrospective cross-sectional study was undertaken to assess the frequency of NFGB group from different clinical specimens and their respective sensitivity pattern from available microbiology Laboratory data of ICare Medical College and Hospital, Haldia, East Midnapur, West Bengal, during the period of one year. Results: Total of 4012 clinical samples were collected from both IPD and OPD of different departments of the college. Clinical specimens of Urine 1104, Pus 1020, Blood 820, Sputum 900, CSF 10, Body fluid 158 were collected. Out of the total 4012 samples, 720 (17.90%) were culture positive. Of which 58(8%) isolates were identified as Non- fermenters. The predominant organisms isolated within Non fermenters were-Pseudomonaspp-38(58.4%) followed by Acinetobacter spp-14 (24.1%), Stenotrophomona spp-4 (6.8%) and Burkholderia spp -2(3.4%). Pseudomona spp were mostly sensitive to Colistin-73.6%, followed by ciprofloxacin-59.8% and piperacillin- tazobactum- and cefepime - 52%. Sensitivity pattern of penems(34-39%) were not encouraging. For Acinetobacter spp, colistin and minocycline were observed to be predominantly sensitive. As Stenotrophomona and Burkholdera spp. are Intrinsically resistant to different group of antibiotics, ceftazidime, penems, minocycline, levofloxacin, co-trimoxazole were selected for AST. Minocycline(65%), Co-trimoxazole (70%),and ceftazidime(55%) were observed predominantly sensitive. Conclusion; Non fermenters group of bacteria are multi drug resistant hence Nosocomial infections are difficult to treat. Selection of antibiotics for AST should exclude the intrinsically resistant group of antibiotics and include specific target group to facilitate therapeutic goal.
Authors and Affiliations
Bharati Ghosh, Kumarjyoti Ghosh, Dinesh kumar
Keywords
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