Study on antibiotic resistance pattern of MRSA among patients in M.G.M. Hospital
Journal Title: Medpulse International Journal of Microbiology - Year 2017, Vol 1, Issue 2
Abstract
Problem statement: The bacterium S. aureus is a common cause of human infection, and it is becoming increasingly virulent and resistant to antibiotics. Our understanding of the evolution of this species has been greatly enhanced by the recent sequences of genome of seven strains of S. aureus. In this present study we shall try to demonstrate and compare the epidemiological features and antibiotic susceptibility pattern of MRSA infection in patients attending the OPDs and IPDs of MGM Medical College and Hospital, Kishanganj, Methods: A total of one hundred fifty isolates of Staphylococcus aureus isolated from various clinical specimens were included in this study. The various clinical specimens were collected from patients attending Outpatient Department Service and patients admitted in the various wards. Results: The identities of these isolates were then confirmed by standard biochemical methods. All the confirmed Staphylococcus aureus strains were subsequently tested for methicillin resistance by disc diffusion method using oxacillin discs (l µg). The antibiotic susceptibility pattern of the MRSA strains as well as the MSSA strains were then determined to a battery of nine antibiotics. The isolates of Staphylococcus aureus were also grouped into biotypes using accepted phenotypic characters. The following observations were made in the study. Conclusion: It may be concluded from study that methicillin resistant Staphylococcus aureus (MRA) is emerging to be a significant problem pathogen with vancomycin probably the only reliable choice for these infection. The prolonged hospital stay, indiscriminate use of antibiotics, lack of awareness, receipt of antibiotic before coming to the hospital are possible predisposing factors of MRSA emergence. Furthermore, unless reduction of the various risk factors specially the indiscriminate use of antibiotic are not checked, the problem may escalate to unmanageable levels.
Authors and Affiliations
Chandan Kumar, Ashok Prasad, Tapas Kumar Bhattacharya, Atanu Roy
Keywords
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