Increasing Trend of Non-Albicans Candida Species in Neonatal Septicemia
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 1
Abstract
Introduction: Neonatal septicemia is a life threatening emergency and delays in diagnosis and treatment may have devastating consequences. With the advance in medical and surgical management Candida species has become the most common pathogen involved in neonatal septicemia. Recently Non-Albicans Candida has emerged as important opportunistic pathogens notably C. tropicalis, C. glabrata, C. parapsilosis etc. Objective: This study was undertaken to know the emerging trend of NAC and importance of species identification of candida. Materials and Methods: During the period of December 2015 to December 2016; blood sample from 141 clinically suspected cases of neonatal septicemia were collected aseptically from NICU at RIMS, Ranchi and were processed by automated BD BACTEC FX system. Only those which yielded pure growth of Candida sp. were included in the study. Identification of Candida sp. was done by using germ tube test, growth on corn meal agar, sugar fermentation test and sugar assimilation test. Results: Out of 141 cases 43(30.5%) were found to be positive for candidemia. Out of 43 cases, Candida albicans were identified in 9 (20.9%) cases while remaining 34 (79.1%) were identified as NAC species. Among NAC species 26/43(60.5%) were Candida tropicalis, 5/43 (11.6%) were Candida glabrata, 3/43 (6.9%) were Candida parapsilosis. This study indicates Candida species as a common cause of nosocomial bloodstream infection. This may be due to various risk factors like increased low birth weight deliveries (93%), prematurity (81.4%), wide use of broad spectrum antibiotics (67.4%), central venous catheters (51.2%), ventilator support (48.8%). Conclusion: As there is increasing frequency of NAC species, species identification becomes important for early diagnosis and treatment of cases, thus reducing the mortality and morbidity.
Authors and Affiliations
Manoj Kumar, Megha Priyadarshini, Ashok Kumar Sharma, Kumari Seema, Amber Prasad
Keywords
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- EP ID EP542778
- DOI 10.21276/ijmrp.2017.3.1.050
- Views 93
- Downloads 0
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