Individualized Hormone Replacement Therapy Versus Ovarian Transplantation
Journal Title: World Journal of Gynecology & Womens Health (WJGWH) - Year 2019, Vol 1, Issue 5
Abstract
Numerous studies conclude that risks and benefits of hormonal replacement therapy (HRT) are dose-dependent [1]. The pharmaceutical industry attempted to partially resolve the issue of individualization of HRT by manufacturing at least six different types of Minivelle patches (0.024mg, 0.0375mg, 0.05mg, 0.075mg, and 0.1mg). The choices offered by the pharmaceuticals are useful but fail to caliber dose based on the needs of the individual patient.Each woman and her physician must decide whether ERT is an appropriate option for her. When making this decision, it is important to consider three factors that affect the risk-benefits of ERT: age at initiation, hormone dose, and route of administration [1]. Estrogen deficiency over a period of many years may result in significant, changes such as bone loss, vaginal and bladder atrophy, and/or other symptoms [1,2]. Therefore, the earlier after menopause ERT is initiated, the better the long-term outcome [1].
Authors and Affiliations
Petrikovsky BM
Keywords
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- EP ID EP609294
- DOI 10.33552/WJGWH.2019.01.000525
- Views 56
- Downloads 0
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