Infection with herpes simplex virus of pregnant women taking the diagnostic possibilities in Poland into account
Journal Title: Ginekologia i Położnictwo medical project - Year 2015, Vol 1, Issue 35
Abstract
Introduction. The human herpesvirus 1 and 2 (HHV-1 and HHV-2) – that is the virus of common herpes is the most common etiological factor for mouth and genital scabs. The risk of more serious consequences of HHV-1 and HHV-2 infection occurs especially in the group of people with lowered immune system capabilities, and also in case of pregnant women and newborn children. Around 2/3 of seronegative women acquires this infection without any symptoms that would suggest herpes. Decisive role for the outcome of the disease is thus played by proper diagnostics and the possibility to introduce early therapy. The aim of the work. The ascertaining of the diagnostic methods used in detection of HHV 1 and 2 infections of pregnant women in Poland and creation of an algorithm for further treatment of a pregnant woman for Human Herpes Virus 1 and/or 2, depending on the state of her immune system. Material and methods. The data was collected in the years 2009-2011. 2625 diagnostic laboratories in the whole country were registered. The source of data was the register of the National Chamber of Laboratory Diagnosticians [Pol. “Krajowa Izba Diagnostów Laboratoryjnych”]. The first stage of research was concerned with selecting those laboratories, from their total number in Poland, that directly perform tests detecting infections with common herpes viruses. The results gathered were subjected to statistical analysis with use of the Statistica 6.1 PL software suite and the SISA tables application. Significance level was adopted at p<0.05. Results. 30 institutions performing tests detecting infections were selected, that is the 1.14% of the total number of laboratories. Hospital laboratories accounted for almost 27% of the investigated institutions, similar was also the number of privately held labs. Sanitary and Epidemiological Service Stations – slightly above 46%. The largest numbers of labs are located in the following provinces: Masovian and Silesian (8,5), Lesser Poland and £ódŸ – 3 each, Lublin and Western Pomerania – 2 each. One lab each was recorded in: Lower Silesia; Kujawy-Pomerania, Lubusz, Opole, Pomerania, Warmia-Masurian, Greater Poland Provinces. Three provinces: Subcarpathian, Podlasie and the Holy Cross have no labs that would enable performing of such tests. Conclusions. The diagnostics of pregnant women infections with Human Herpes Virus 1 and/or 2 is most often performed with use of ELISA method. The methods based on PCR and their variations are only used in few labs in Poland. The lack or the small number of laboratories performing Human Herpes virus infections makes the detection of infections of pregnant women difficult.
Authors and Affiliations
Agnieszka Wyrozębska, Ewa Dmoch-Gajzlerska, Urszula Jurkowska
Keywords
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