Influence Exogenous Factors on Genomic Imprinting 1. Effect of Nutrition and Provision of Micronutrients in Mother on Genomic Imprinting Descendants
Journal Title: Здоров`я дитини - Year 2016, Vol 5, Issue 73
Abstract
The article analyzes the impact of maternal nutrition during pregnancy on the forming of genomic imprinting in the fetus. It was shown that changes in DNA methylation of imprinted genes, induced by infringement of providing protein and micronutrients, are accompanied by abnormalities of physical development and increased risk of chronic inflammatory diseases, diseases of the cardiovascular system, the metabolic syndrome in the child’s postnatal life. It is emphasized that in order to prevent the development of imprinting-associated disease in a child special attention should be paid to the adequate content of protein, folic acid, methionine and group B vitamins in diet of pregnant women while forming their diet.
Authors and Affiliations
A. Ye. Abaturov, M. S. Moroz
Keywords
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- EP ID EP191976
- DOI 10.22141/2224-0551.5.73.2016.78322
- Views 54
- Downloads 0
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