Influence of Hepatitis B and Hepatitis C Virus Infections and Human Immunodeficiency Virus Therapy on Liver Status of Patients with Human Immunodeficiency Virus
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 11, Issue 7
Abstract
Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) are emerging among Human Immunodeficiency Virus (HIV) patients. Aim: To determine the impact of the presence of hepatitis B and hepatitis C viral infections as well HIV treatment on the liver of patients with HBV, HCV and HIV co-infections. Methods: A descriptive, cross-sectional study on 115 HIV patients that were subdivided into two groups; group A included 67 patients who had HIV mono-infection and group B included 48 patients who had HIV plus HBV, HIV plus HCV or HIV plus both. Results: 48 HIV patients (41.7%) had HBV and/or HCV infections. 4 patients (3.5%) were positive for HBV Surface Antigen (HBsAg), 37 patients (32.2%) were positive for HCV Anti-body (Anti-HCV Ab) and 7 patients (6.1%) were positive for both. HIV treatment caused significant impairment of liver functions especially in group B patients. CD4+ T Lymphocytes significantly increased after HIV therapy in group A versus group B. Conclusion: HIV may accelerate liver damage caused by HBV and HCV. HIV therapy carries a potential risk for hepatotoxicity.
Authors and Affiliations
Tary Abdel-Hamid Salman, Khaled Mohammad Attallah, Omkolsom Mohamed EL-Haddad, Azza Mohamed Abdel-Latif, Mohamed Abdou Awid
Keywords
Related Articles
- EP ID EP340163
- DOI 10.9734/BJMMR/2016/19183
- Views 51
- Downloads 0
Radiographic Prevalence and Clinical Significance/ Etiology of Elongated Styloid Process in Females
Aims: The aim of the present study was to investigate the radiographic prevalence of elongation and calcification in styloid complex and its clinical significance and etiology in female patients attending Taibah Universi...
Evaluation of Oral Clonidine Premedication on Intraoperative Blood Loss and Bleeding Severity Score in Functional Endoscopic Sinus Surgery – A Prospective Placebo Controlled Study
Background: Bleeding during functional endoscopic sinus surgery (FESS) remains a challenge for both surgeons and anaesthesiologists despite several modalities available for improving the surgical field. This study was co...
Research of HLA II Class DRB1, DQA1, DQB1 Genetic Markers in Patients with HIV Infection and AIDS
Aims: To find out the most frequent associations of the HLA II class loci DRB1*, DQA1*, DQB1* with the HIV/AIDS infection. Place and Duration of Study: The study took place in The Laboratory of Clinical Immunology and...
From Faulty Biochemical Assumptions to Poor Diagnostic Performance: Reflections on the Failure of DNA Microarrays to Become a Reliable Clinical Diagnostic Tool
Since their inception about two decades ago, DNA microarrays have been considered as a great hope in translational research and personalized medicine. Although DNA microarrays for gene expression profiling proved to be a...
The Awareness of Asthma and COPD among Religious Officials
Aim: Religion has an important role for coping with various medical conditions and serious diseases. Chronic airway diseases such as asthma and COPD are associated with morbidity and mortality in our country. The aim of...