INFLUENCE OF HYDROPHILIC POLYMERS ON THE PROPERTIES OF GYNECOLOGICAL POWDERS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2015, Vol 0, Issue
Abstract
Tested impact of polyvinyl alcohol, dextrane and calcium alginate for the properties of the powders containing poloxamer 407 and lactic acid complexed with chitosan. For researches was prepared formulations with different pH and rheological properties. The thermosensitive gels obtained from thermosensitive powders possess the work of adhesion with different values. The researches revealed that the dynamic viscosity of the gels obtained from powders is high. A wide range of pH of the thermosensitive gels allows the selection of the optimum formulation. The gels obtained from the powders containing polyvinyl alcohol or dextrane or calcium alginate were characterized by the specific dynamic viscosity. The researches demonstrated that the methylcellulose with different values of the viscosity with poloxamer 407 significantly affect the adhesive properties of thermosensitive hydrophilic gels obtained from powders.
Authors and Affiliations
Katarzyna Małolepsza-Jarmołowska
Studies on the Dyeing of Chitin and Chitosan with pre-metallised Dyes at Neutral pH
Both 1:1 pre-metallised acid dyes and pre-coppered direct dyes, but not 1:2 pre-metallised acid dyes, have been shown to readily dye chitin and chitosan from neutral dyebaths. With the 1:1 pre-metallised acid dyes the ad...
ADSORPTION OF BASIC YELLOW 28 (BY 28) AND ACID YELLOW 23 (AY 23) DYES ONTO CHITIN
The present study investigated the sorption of Basic Yellow 28 (BY 28) and Acid Yellow 23 (AY 23) by chitin flakes. The study determined the influence of pH value on adsorption effectiveness and the adsorption capacity o...
CHARACTERIZATION OF WATER STATE IN CHITOSAN HYDROGEL MEMBRANES
In this study, the structure of hydrogel chitosan membranes was investigated. To determine the structure of hydrogel membranes the Differential Scanning Calorimetry (DSC) was used. On the basis of DSC spectra the enthalp...
TECHNOLOGY OF PREPARATION AND EVALUATION OF KETOPROFEN-CHITOSAN SOLID DISPERSION
The aim of the study was to investigate the effect of chitosan on the dissolution of ketoprofen incorporated into this polymer carrier. The study investigated ketoprofen in physical mixtures at the drug to polymer ratios...
THE EFFECT OF POLOXAMER 407 ON THE PROPERTIES OF HYDROPHILIC GELS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN
Anatomical and physiological conditions in the vagina do not facilitate easy application of the drug neither its maintenance on the site of application. Insufficient duration of the drug’s contact with vaginal mucosa doe...