Influence of Immediate and Long Term Effects of Repetitive Transcranial Magnetic Stimulation Combined with Speech Therapy on Post Stroke Nonfluent
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 10
Abstract
Background: A high proportion of patients who have suffered a stroke also suffer from aphasia. The aim of this work was to determine and investigate immediate and long term effects of repetitive transcranial magnetic stimulation combined with speech and language exercise therapy on non fluent motor aphasia (Broca's aphasia) in chronic cerebrovascular stroke. Methods: Forty chronic cerebrovascular stroke patients represented the sample of the study. Their age ranged from 45 to 60 years. The patients were assigned randomly into two equal groups; study group (G1) and control group (G2). The patients in both groups received the same medical and physical care during treatment period to avoid any complications. The study group treated by selected speech exercises combined with rTMS. Different domains of speech function (repetition, reading, naming, writing, comprehension and spontaneous speech) were assessed by the Arabic translated form of the modified Chesher test and Token test of Aachen aphasia test (AAT). Power of stimulation intensity of rTMS (represents 90% of the resting motor threshold that recorded from contraction of the first dorsal interosseus of the unaffected hand) were measured pre, post and after three months of the end of the treatment to determine level of brain excitability. The results: At the end of the treatment there was a significant improvement in all domains in (G1) of the Arabic translated form of the modified Chesher test. In the control group (G2) there was a change in total score of the Arabic translated form of the modified Chesher test in approximately all domains but not reach www.jmscr.igmpublication.org Impact Factor 3.79 ISSN (e)-2347-176x Moshera H. Darwish et al JMSCR Volume 02 Issue 10 October 2014 Page 2488 JMSCR Volume||2||Issue||10||Page 2487-2504||October-2014 2014 to significance level (P<0.05) except auditory comprehension and pantomime there was a significant increase (P>5). Comparison of mean values of all domains of (G1) and (G2) post treatment indicate significance improvement of all different domains measured by clinical tests or rTMS in (G1). A significant decrease in the mean value of power intensity of rTMS post treatment in (G1) was observed (P<0.05). There was a Strong negative correlation between improvements in total score of the Arabic translated form of the modified Chesher test and the decrease of the mean values of power intensity of rTMS in (G1). Conclusion: Speech exercises combined with rTMS permit the mechanisms of transcortical disinhibition to enhance language function in chronic non- fluent aphasia post stroke patients. Low frequency rTMS delivered over Broca's area could improve language by enhancing long-term potentiation and synaptic plasticity within the stimulated areas involved in language network.
Authors and Affiliations
Moshera H. Darwish
Keywords
Related Articles
- EP ID EP207860
- DOI -
- Views 44
- Downloads 0
Eventration of Diaphragm – An Incidental Rare Entity
The eventration of diaphragm is a rare entity characterized by uniform elevation of part or parts of both hemi-diaphragms associated with ascent of abdominal organs like intestine showing haustrations under the diaphragm...
Clonidine as an Adjuvant to 0.5% Ropivacaine for Supraclavicular Brachial Plexus Block in Patients Undergoing Orthopedic Surgery of Forearm and Hand - A Randomized Controlled Trial
Background: Regional anesthesia blocks are being increasingly used to cater to the variety of surgical procedures for the forearm and hand. Methods to enhance the duration of analgesia and shorten the onset and lengthen...
Prevalence of Drug Utilization Patterns on Hypertensive Patients in Tertiary Care Hospital
Introduction: A Prospective Study on Prescribing Pattern and Utilization of Anti-Hypertensive Drugs in A Tertiary Care Teaching Hospital Method: The Prospective observational study was conducted in Department of pharmaco...
Spectrum of Alcohol-Related Morbidities in Patients Presenting to Medical Emergency
Background: Alcohol dependency and alcohol abuse is a major health care objective being faced by doctors during emergency services. Prompt specialized examination, pathological examination and social therapy should be in...
The prognostic value of left atrial function assessed by TDI after myocardial infarction (comparison between ST and non ST segment elevation myocardial infarction)
Aim: The aim of this study is to assess the predictive value of LA function by TDI for assessment of the prognosis of patients with ST and non ST segment elevation (NSTE) myocardial infarction (MI). Methods and Results:...