Influence of NK Cells during Epithelial to Mesenchymal Transition in Oral cancer
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 7
Abstract
Oral carcinogenesis is a major health problem in the world. Over 90% of all Oral Cancer is classified as Oral Squamous Cell Carcinoma with loco regional relapse and cervical lymph node metastasis.Considering epithelial malignancies, the role of immune system in governing Epithelial to Mesenchymal Transition (EMT) has not been much investigated in oral cancer. The present investigation suggests a possible role of NK cells during EMT and its correlation to invasive properties of tumour. Athough a direct correlation couldn’t be established but the influence of NK cells on EMT could be seen which open up new horizon for immunotherapeutic strategies in the coming years.
Authors and Affiliations
Priyashi Rao
Keywords
Related Articles
- EP ID EP517426
- DOI -
- Views 96
- Downloads 0
Premature Rupture of Membranes-Clinico Epidemiological Perspective
Background: Aim of the study is to compare demographic data, study the outcome of pregnancy in patients with Premature Rupture of Membranes (PROM) and establish correlation between latency of PROM with outcome of pregnan...
Significance of Inter-Ictal Period in Detection of Epilepsy by EEG
Objectives: To evaluate the sensitivity of EEG in diagnosing Epilepsy in different inter-ictal periods. Materials and Methods: The study was done from June 2014 to May 2015.One hundred and thirteen clinically diagnosed c...
Comparison of PASI and DLQI among Out-Patients Andin-Patients with Psoriasis in a Tertiary Care Centre
Psoriasis is a chronic condition strongly affecting social stigmatization, comfort, physical disability and psychological distress. It is important to define the severity of psoriasis, but it is also important to identif...
A Rare Case of Invasive Mole with Silent Uterine PerforationA Case Report
Invasive mole is a condition where the trophoblastic tumour invades the myometrium that may erode into the uterine vessels, causing massive intraperitoneal haemorrhage. Normally it gets detected by ultrasonography, confi...
A Study on Atopy, Contact Sensitization and Hand Eczema
Background: Atopic dermatitis and hand eczema are common chronic and relapsing inflammatory skin conditions that often co-occur. Many factors like age of onset, personal and family history of atopy and severity atopic de...