Influence of Type 2 Diabetes and the Sex on the Occurrence of Sub-Clinic Left-Ventricular Diastolic Dysfunction of the Heart
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2012, Vol 5, Issue 3
Abstract
Aims: To test the hypothesis that: the potential of type 2 diabetes, in precipitation of the sub clinical left ventricular diastolic dysfunction at the female sex, in absence of high blood pressure disease, coronary disease and other known heart disease, is different in comparison to the male sex. Material and Methods: Prospectively, 180 people with type 2 diabetes were tested, at the ages between 45 and 55, divided into 2 groups: 1) Control group- was comprised of 60 patients (30 male and 30 female), without diabetes, with similar epidemiological-demographic characteristics; 2) Diabetes group - was comprised of 120 patients (60 women and 60 men) with type 2 diabetes. The estimation of the diastolic function of the left ventricular was made by Doppler echocardiograph analysis of the diastolic time intervals, as well as analysis of the model of ventricular filling, shown with a transmitral flow-velocity profile, acquired with a conventional pulsed-wave Doppler. Results: Significant changes between the groups in clinical variables were observed regarding body mass index, low density cholesterol and triglycerides, the variables gotten with the pulsed-wave Doppler of the transmitral flow, and the duration of the isovolumetric relaxation time. Conclusions: In this study, we do not prove the hypothesis that the type 2 diabetes potential in the precipitation of the sub clinical left ventricular diastolic dysfunction at the female sex, in absence of coronary disease, blood pressure disease and other well known heart diseases, is different in comparison to the male sex.
Authors and Affiliations
Ylber Jani| PHO ”Heart Diagnostic”, Debar, Republic of Macedonia, Verka Spiroska| University Clinic of Cardiology, Faculty of Medicine, University ”Ss Cyril and Methodius“, Skopje, Republic of Macedonia
Keywords
Related Articles
- EP ID EP8876
- DOI 10.3889/MJMS.1857-5773.2012.0253
- Views 343
- Downloads 16
Ocimum Gratissimum Linn Causes Dose Dependent Hepatotoxicity in Streptozotocin-Induced Diabetic Wistar Rats
Aim: Hepatoprotective effects of Ethanolic extract Ocimum gratissimum leaves (O. gratissimum) in streptozotocin-induced diabetic rats was studied. Material and Methods: Thirty-six adult rats were assigned into six grou...
Effects of the Pharmacological Pre-treatment and Global Brain Ischemia on the Body Temperature in Experimental Rats
The aim of this study is to examine the influence of the pharmacologic pre-treatment and global brain ischemia on the one hand, and on the other hand, the influence of anaesthesia on the body temperature in experimenta...
Macedonian Medical Doctor of Philosophy (PhD) Theses Defended in 2008
We present abstracts of PhD theses defended in 2008 at the Faculty of Medicine, University “Ss Kiril and Metodijâ€, Skopje, Republic of Macedonia. English summaries are published as they are translated by authors an...
Prevalence of Otitis Media in Okada Community, Edo State, Nigeria
Aim. To determine the prevalence of otitis media in Okada, a rural community in Nigeria, and the effect of age and gender on its prevalence as well as susceptibility profile of the bacterial agents in the community. M...
The Impact of Social Assistance Programs on Reducing Inequities in Health Care Among Vulnerable Groups in the Republic of Macedonia (A Small Scale Descriptive Study)
Aim. The aim of this research was to look at the impact of social assistance programs on reducing social inequities in health care among the vulnerable groups in Macedonia. Materials and methods. A small scale descrip...