Inguinal sarcoidosis– an Unusual Presentation
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2016, Vol 6, Issue 9
Abstract
Sarcoidosis is a chronic multisystemic disorder of unkown etiology. It is characterised by non caseating granulomas with pulmonary involvement, bilateral, in 90% cases. Hilar or paratracheal pulmonary lymphnodes are often enlarged. The disease also affects certain extra-pulmonary sites like liver, spleen (20%), joints, skin, eye and bone marrow1. This is a case report of a rare case of extra-pulmonary sarcoidosis, involving the inguinal lymph nodes,a rare site of occurrence as such. A 35-year-old female presented with a large solid diffuse lump in left thigh for 3 months. Clinically, it appeared to be a soft tissue tumour. On FNAC, smears were paucicellular and only few spindle cells against a haemorrhagic background were seen. MRI showed multiple enlarged inguinal lymph nodes on the left side of the thigh. On CT, bilateral hilar lymphadenopathy was seen. Post excision lump on histopathological examination revealed, characteristic Schaumann bodies and asteroid bodies with multiple confluent non caseating granulomas, and a diagnosis of sarcoidosis was made. The case was finally diagnosed as extrapulmonary sarcoidosis of the inguinal region, which as such is a rare site for nodal involvement.
Authors and Affiliations
Neema Tiwari, Nishi Tandon, Nirupama Lal, Vibhore Mahendru
Personalized Medicine Phenytoin Therapy
Phenytoin is one of the antiepileptic drugs most widely prescribed. This drug has narrow therapeutic index, and often treated for a long time. Phenytoin was metabolized by CYP2C9 (major) and CYP2C19 (minor). The purpose...
Cardioprotection of a Novel Danshensu Derivate Against Oxidative Injury and Mitochondrial Dysfunction in Vitro and Myocardial Ischemia/Reperfusion Injury in Rat
Objectives Myocardial ischemia/reperfusion injury remains an important clinical problem in the world. Extensive research have focused on strategies for attenuating myocardial ischemia and reperfusion injury. Danshensu (D...
Dual Role of Endophytic Fungi from the Roots of Terminalia arjuna (Roxb.) Wight & Arn
Plant endophytes constitute different crucial parts of microbial differences. Plant endophytic fungi are an imperative and novel asset of natural bioactive metabolites with their different potential applications in diffe...
Identification of Strain H41-55 and Chemical Constituents from its Fermentation Broth
The strain H41-55 was identified as Streptomyces antibioticus according to morphological, cultural, and physiological and biochemical characteristics in combination with 16S rDNA sequence and phylogenetic tree analysis o...
Role of Pathological Organisms in Gallstone Disease
Background Gallstone disease is the commonest disease in India. Patients present with pain abdomen and nausea and vomiting. This study deals with etiology, pathogenesis including the role of bacteria in the formation of...