Insight into the exocrine pancreatic function (serum amylase and lipase) in type 2 diabetes mellitus
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction Insulin has its effect on the basal and stimulatory secretion of exocrine pancreatic enzymes In this context this study has been done to understand the relationship between the exocrine and endocrine entities of pancreas by analyzing two most commonly estimated exocrine enzymes serum amylase and serum lipase in type 2 DMMaterials and Methods The study was conducted at Rajarajeswari Medical College and Hospital Bengaluru Karnataka from January 2012 to December 2012 Hundred clinically diagnosed cases of type 2 diabetes mellitus Fifty well controlled HbA1c 7Results Serum amylase and serum lipase levels were within the reference range in all the three study groups There was no significant difference in serum amylase among well controlled and poorly controlled type 2 DM In contrast significant difference in serum amylase levels was observed between diabetic group and controls pConclusion The potential underlying connection between exocrine and endocrine function of pancreas in patients with type 2 DM needs further investigation with larger population to consider the analysis of serum pancreatic enzymes especially serum lipase levels as an additional informative parameter to assess the glycemic control in type 2 DMKeywords Type 2 DM Serum amylase Serum lipase
Authors and Affiliations
Manjula K. S. , Reena R, Usha S. M. R. , Priyadarshini K. S. , H. V. Shetty
Keywords
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- EP ID EP475182
- DOI 10.18231/2394-6377.2018.0079
- Views 61
- Downloads 0
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