Insilico gene expression and protein structure a comparative study on polycystic ovarian syndrome and ovarian cancer in human beings using bioinformatics
Journal Title: International Journal of Novel Trends in Pharmaceutical Sciences - Year 2015, Vol 5, Issue 3
Abstract
Ovarian cancer is a cancer that begins in an ovary. It results in abnormal cells that have the ability to invade or spread to other parts of the body. Polycystic ovary syndrome (PCOS) is a set of symptoms due to a hormone imbalance in women. PCOS is due to a combination of genetic and environmental factors. The aim of our present research investigation is to focus on gene expression and molecular structural relationships between Polycystic Ovarian Syndrome and Ovarian Cancer using advanced Insilico protocols. We identify the protein targets YAP1 (Yes Associated Protein 1) and FILIPIL (Filamin A Interacting Protein 1 Like) which are potential drug target for Polycystic Ovarian Syndrome and Ovarian Cancer. The three dimensional structure comparison studies clearly show that the two proteins target have similar sequence and structure. The identified protein target and Insilico gene expression studies would be useful in the field of clinical oncology.
Authors and Affiliations
Surya Prabha. U , Sakila. L , Balaji. M
Keywords
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