Interpretation of doxycycline+chloroquine dual therapy for A. phagocytophilum infection in dogs
Journal Title: Revista MVZ Cordoba - Year 2015, Vol 20, Issue 2
Abstract
Objective. A. phagocytophilum, an obligate intracellular pathogen, is a well-known agent causing granulocytic infections in both animals and humans. The purpose of the present study was to describe clinical course and consequences of Canine Granulocyctic Anaplasmosis among dogs in Aydin province, Turkey with special reference to hematological alterations and possible interpretations of doxycycline+chloroquine dual therapy. Materials and methods. A controlled clinical trial was carried out on 14 dogs referred and diagnosed as Canine Granulocyctic Anaplasmosis within Snap 4dx test. Relevant haematological data were recorded before (day 0) and after treatment (day 30) in both groups. Group I (n=7) were adminestered doxycycline (10 mg/kg q 12 h via oral route for 14 days) and chloroquine (2.5 mg/kg q 12 h for 14 days) and group II (n=7) received only doxycycline (10 mg/kg q 12 h for 14 days via oral route) therapy. Results. Doxycycline treatment hasten resolution of clinical signs in all dogs in about 2 to 7 days. There was no statistically significant differences among hematological variances detected (p>0.05). Conclusions. It may suggest that in conjunction with doxycycline chloroquine may have helped to speed up relevant clinical signs of CGA.
Authors and Affiliations
Kerem Ural, Ph. D. | Adnan Menderes University, Faculty of Veterinary, Department of Internal Medicine, Isikli, Aydin, Turkey.Corresponding: uralkerem@gmail.com
Keywords
Related Articles
- EP ID EP3400
- DOI -
- Views 436
- Downloads 17
Evaluation of first feeding of capaz larvae Pimelodus grosskopfii under laboratory conditions
Objective. Evaluate the performance and survival of capaz larvae Pimelodus grosskopfii after supplying live food (Cladocera, Copepod and Artemia Salina). Materials and methods. Capaz larva were placed in plastic containe...
An age structured model for obesity prevalence dynamics in populations
Objective. Modeling the correlation of the development of obesity in a population with age and time and predict the dynamics of the correlation of the development of obesity in a population with age and time under differ...
APPLICATIONS OF FLOW CYTOMETRY IN MICROBIOLOGY VETERINARY SCIENCE AND AGRICULTURE
Flow cytometry, an automated, multiparametric and quantitative method, analyzes the scattering and fluorescence signals produced as series of single cell pass through a laser beam. The potential of the new methods of ana...
Antibodies against spotted fever group Rickettsia sp., in horses of the colombian Orinoquia
Objective. It was determined the presence of antibodies against Rickettsia sp. of the spotted fever group, in horses of 8 municipalities of the Colombian Orinoquia. Matherials and methods. A cross-sectional study was con...
Effect of age and coasting period on oocytes quality and their in vitro development from prepubertal cattle
Objective. This study evaluated the effect of age and coasting period over oocyte quality and their posterior development under in vitro conditions from prepubertal Bos indicus crossbred donors. Material and methods. Don...