Interrelationship of corneoscleral rigidity, corneal thickness and target IOP levels in patients with unstabilized POAG
Journal Title: Офтальмологический журнал - Year 2018, Vol 0, Issue 5
Abstract
Background: To the best of our knowledge, no strict criteria for estimating the probability of glaucomatous progression have been reported. Purpose: To investigate the interrelationship between corneoscleral rigidity, corneal thickness, and target IOP in patients with stage 1 or 2 of unstabilized primary open-angle glaucoma (POAG). Materials and Methods: Patients underwent routine eye examination for glaucoma. In addition, Pascal dynamic contour tonometry and ocular blood flow tonography were performed, corneoscleral rigidity was determined, and target IOP was calculated. Results: Patients with unstabilized POAG were divided into two groups. Group 1 involved 9 patients (8 patients and 1 patient with stage 1 and stage 2 of POAG, respectively) whose tonometer IOP was higher than true IOP, and Group 2 involved 14 patients (1 patient and 13 patients with stage 1 and stage 2 of POAG, respectively) whose tonometer IOP was lower than true IOP. In the former group, corneoscleral rigidity values were one order of magnitude higher than those in the latter group. It is likely that the corneoscleral rigidity in eyes with stage 1 of unstabilized POAG is substantially higher than that in eyes with stage 2 of unstabilized POAG. It was noted that patients with stage 2 of POAG had low central corneal thickness of 460 μm to 515 μm. It was found that a comparatively low target IOP of 12.7 mm Hg to 13.0 mm Hg was required for patients with a rather high corneoscleral rigidity (-2.3 mm Hg, -0.7 mm Hg, 3.1 mm Hg, 6.8 mm Hg, 6.9 mm Hg), and a comparatively high target IOP of 14.2 mm Hg to 14.6 mm Hg was required for patients with lower corneoscleral rigidity (-5.5 mm Hg, -3.2 mm Hg, -1.5 mm Hg, -4.9 mm Hg, 0.8 mm Hg). Conclusion: Absolute values of target pressure required for stabilization of POAG in patients with high corneoscleral rigidity are 10.7% lower than those for patients with low corneoscleral rigidity, and this difference is statistically significant.
Authors and Affiliations
O. Peretiagin, S. Dmytriiev, Yu. Lazar
Keywords
Related Articles
- EP ID EP424971
- DOI 10.31288/oftalmolzh201852631
- Views 71
- Downloads 0
Efficacy of 810-nm diode laser transpupillary thermotherapy delivered using the methodology developed for small (T1) choroidal melanomas
Background: Diode laser transpupillary thermotherapy (TTT) used as a monotherapy may be a treatment of choice for small choroidal melanomas (CM). We developed the methodology for performing TTT, which involves four sessi...
Changes in incidence rates of retinopathy of prematurity in Odessa region in the years of 2009 to 2016
Background. Although retinopathy of prematurity (ROP) is a wide-spread disease, statistical data are absent; so studying the incidence of ROP in Ukraine is of importance. Purpose. To study the incidence of retinopathy...
The level of pediatric cataract in regions according to data of Ministry of Health of Ukraine for 2007-2016 years
The purpose of this study was to examine the changes in incidence and prevalence of cataract during the 10-year period between 2007-2016 among children who had been registered in the Health Care of Ukraine. In Ukraine, t...
A case of successful using a stromal corneal transplant for therapeutic keratoplasty in a patient with herpetic keratitis
E-mail: evsereda08@gmail.com Introduction. Herpes virus infection is a cause of inflammatory corneal diseases in 20-57 % of cases. To date, due to the lack and high cost of donor material in Ukraine, approbation of new...
Efficacy of morpholinium-methyl-triazolyl-thioacetate (thiotriazolin) for neurotrophic keratoconjunctivitis in long-term silicone hydrogel contact lens wearers
Background: Vision correction with contact lenses offers some clear advantages as compared to correction with spectacles, but has some negative effect on the eye, too. Individuals wearing soft contact lenses (SCL) for ye...