Intra articular Injection of Rifampin in Iranian Children with Haemophilic Arthropathy
Journal Title: Iranian Journal of Blood and Cancer - Year 2010, Vol 2, Issue 3
Abstract
Background: Chronic synovi tis is one of the most important complications in haemophilic patients. Rifampin is an antibiotic which its intra-articular injection leads to destruction of the synovial membrane of hemophilic patients medically. Materials and Methods: Between September 2003 and November 2005, we administered intra-articular rifampin in 16 hemophilic joints of 8 hemophilic patients. Results: Median age of our patients was 14.5 year-old. There were 11 knee joints and 5 elbow joints. After treatment we observed significant improvement in treated joints. Conclusion: This study reveals that intra-articular injection of rifampin may improve arthropathy in hemophilic patients.
Authors and Affiliations
Peyman Eshghi, Kourosh Goudarzipour, F. Hoorieh Davoudabadi, Roxana Aghakhani
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