Intra articular introperative morphine causes increased postoperative demand and after total knee replacement
Journal Title: Journal of Medical Science and Technology - Year 2015, Vol 4, Issue 2
Abstract
Objective of the study was to assess the postoperative pain relief influence of intraoperative intra-articular morphine after total knee replacement. This prospective, double-blind and randomized study included 103 patients of both sexes, aged 46-75 years, classed I-III physical status by the American society of anesthesiologists and scheduled for total knee replacement for chronic osteoarthritis at Prince Hashim hospital, Zarqha, Jordan, during the period April 2014-March 2015. Patients were assigned randomly into two groups. Group I (n=60), patients received a mixture of 10 mg of morphine (1 ml) and 9 ml of normal saline(0.9%) and group II (n=43),patients received 10 ml of normal saline (0.9%). Postoperative morphine administered in the first 24 hours was registered. Postoperative pain was evaluated using the visual analog pain scale 0-10, at 1 and 24hours after surgery. Student’s t test and Chi-square test were used to test statistical significance where P value less than 0.05 was considered significant. There were no significant differences between the two groups regarding the period of admission in hospital or the pain score at postoperative 1 or 24 hours. Patients in group I, received significantly more morphine in the first postoperative 24 than in group II. Intra-articular intraoperative morphine administration has no significant analgesic postoperative effect.
Authors and Affiliations
Khaled Al-issa, Raid Al-smadi, Ethar Ibrahim , Anan Qabha
Keywords
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