Intracystic papillary carcinoma of breast- A rare disease entity in males
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
Carcinoma of breast is rare in men with an estimated incidence of one per 100000 per annum Of all the histological types of breast cancer Intracystic papillary carcinoma IPC of the breast is rare accounting for less than 1 of all breast malignancies A 61 year old gentleman presented with painless progressively enlarging lump in his left breast since 3 years associated with serosanginous nipple discharge of 3 months duration On examination a single 8 x 3 cm well defined cystic swelling in the retroareolar region was felt with normal overlying skin and nippleareola complex No axillary lymph nodes were palpable FNAC of the lump showed features of infiltrating ductal carcinoma Patient was taken up for modified radical mastectomy under general anaesthesia Histopathological examination of the specimen revealed a cyst measuring 7x4 cm containing hemorrhagic fluid On gross examination the cyst wall exhibited grey white papillary excrescences that protruded into the lumen Histopathological diagnosis of intracystic papillary carcinoma was given Being a rare entity there is no definite guideline for the treatment of IPC however a surgical excision with a clear resection margin forms the mainstay of the treatment These patients have very good outcome The addition of hormonal treatment does not appear to have an impact on the patient outcomeKeywords Intra cystic Papillary Male Breast carcinomanbsp
Authors and Affiliations
Afnan Gul, Sandhyalakshmi B. N, Srinivasa Murthy V
Role of glial fibrillary acidic protein (GFAP) marker in central nervous system lesions
Introduction: The subject of tumours of the nervous system is often looked upon with apprehension by medical practitioners as central nervous system tumours constitute 1-2% of all the neoplasms. Gliomas constitute 38.7%...
Immunohistochemical expression of Ki-67 in gall bladder carcinoma
Introduction Gall bladder carcinoma accounts for 0307 of all cancers and has a peak incidence among women aged 70 and 79 years Recently many molecular markers like Ki67 cyclin D1 MUC1 and p53 with prognostic impact on GB...
Study of clinicomorphologic spectrum of prostatic lesions and correlation with prostate specific antigen levels in a tertiary care center
Introduction: Benign and malignant lesions of prostate are some of the commonest problem of elderly men age group. Prostate specific antigen level, histopathological examination, and digital rectal examination are consid...
Assessment of the quality of fresh frozen plasma and refrozen thawed fresh frozen plasma – A prospective study at a tertiary care teaching hospital in Chennai
Introduction FFP contains the labile as well as stable components of the coagulation fibrinolytic and complement systems The use of plasma and its products has increased manifold over the four decades In blood transfusio...
Distribution of head and neck lesions diagnosed on histopathology in Western U.P.: A retrospective study
Introduction Head and neck lesions are very common in day to day practice These diseases range from common cold to the uncommon malignant neoplasms These lesions are responsible for very high morbidity and mortality Fact...