Intraosseous implants of Resilon and gutta-percha in rats: a histopathological evaluati
Journal Title: RSBO - Year 2010, Vol 7, Issue 4
Abstract
Introduction: Root canal system obturation uses filling materials and sealers that should present, among other proprieties, a biocompatibility to the periradicular tissues. Objective: To compare, in vivo, bone tissue response to two types of biomaterials: Resilon points and gutta-percha points. Material and methods: For this purpose, 40 male albino Wistar rats were used for implantation of the biomaterial points in their previously perforated left tibia. Twenty rats received gutta-percha point implants and the other 20 rats received Resilon point implants. All animals had their right tibia partially perforated, as a control group. At the end of the 2nd, 4th, 8th and 16th week post-implantation, bone tissue samples were taken for analysis. Histological sections were stained by HE, photographed, and morphologically analyzed using TPS Dig 1.38 software. Tissue response was analyzed, taking into consideration the periosteum thickness variation in the formed bone callus area. Results: Data were statistically analyzed by ANOVA, followed by Tukey’s test (p <0.05). There was no statistical difference between the materials tested, when the periosteum thickness was analyzed. Conclusion: Both Gutta- percha and Resilon points were biocompatible and well tolerated when implanted in bone tissue of rats.
Authors and Affiliations
Pedro Barros, Rodrigo Cunha, Gustavo Silva, Mariana Quinália, Aline Ireno, Carlos Bueno
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