Intrathecal Nalbuphine versus Intrathecal Dexmedetomidine for Postoperative Analgesia of Lower Abdominal and Lower Limb Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 3
Abstract
ntroduction: Opioids are used as adjuncts with the local anaesthetic for longer duration of action and better postoperative analgesia [4]. Nalbuphine, is a mixed agonist-antagoniste and its analgesic potency is equal to morphine and less side effects like respiratory depression, urinary retention and pruritus. Intrathecaldexmedetomidine increased the duration of analgesia. Aim: To compare the duration of postoperative analgesia and the incidence of side effects of intrathecalnalbuphine and intrathecaldexmedetomidine for lower abdominal and lower limb surgeries. Materials& Methods: 60 patients of ASA I & II, underwent lower abdominal and lower limb surgeries using spinal blockade included. Group I (n=30) patients received Inj. Bupivacaine heavy 15 mg with Inj. Nalbuphine 0.8 mg. Group II (n=30) patients received spinal anaesthesia with Inj. Bupivacaine heavy 15 mg & Inj. Dexmedetomidine (5 mics) Results: The mean onset of sensory block (3.5±0.7 Vs 4.2±0.8) and motor block (1.7±0.7 Vs 2.6±0.9). Both were shorter in nalbuphine group which was statistically significant. The mean duration of analgesia was longer in patients who received dexmetomidine (197±6 min Vs 99.6±6 min), Incidence of hypotension and bradycardia were higher in dexmetomidine group but amenable to medical management. Conclusion: Intrathecalnalbuphine (0.8mg) decreases the mean duration of onset of both sensory and motor block. Intrathecaldexmedetomidine prolongs the duration of analgesia but the incidence of bradycardia and hypotension are higher.
Authors and Affiliations
Manisha Kanagarajan
Keywords
Related Articles
- EP ID EP472136
- DOI 10.21088/ijaa.2349.8471.4317.50
- Views 58
- Downloads 0
A Comparative Study of Efficacy of Fentanyl Versus Buprenorphine as an Adjuvant to Bupivacaine in Lower Abdominal Surgery
Background: Pain poses a unique challenge to anesthesiologist. Continuous unrelieved pain activates the pituitary adrenal axis which can suppress the immune system resulting in postsurgical infection and poor wound heali...
Efficacy of USG-Guided Bilateral Subcostal Tranversus Abdominis Plane Block and Conventional Port Site Infiltration after Laparoscopic Cholecystectomy: A Prospective Randomised Controlled Study
Aim and objectives: This prospective, randomised, single blinded controlled study evaluated and compared the efficacy of Bilateral subcostal USG- guided Transversus Abdominis muscle plane block to the Conventional Port s...
Anaesthetic Management of a Case of Severe Pulmonary Artery Hypertension for Excission of A Vulval Mass
It is known that patients with pulmonary hypertension are at high risk for anaesthesia and surgery. Primary pulmonary hypertension (PPH) has now been replaced byidiopathic pulmonary hypertension or pulmonary artery hype...
Effect of Adding Potassium Chloride to Bupivacaine in Brachial Plexus Block: A Cross Sectional Case Control Study
Brachial plexus blockade for upper limb surgeries is the most common major peripheral nerve block technique and a significant difference exists between the onset times of various agents when these blocks are used. Adjuva...
Study of Prescription Pattern of Analgesics in Terminally Ill Cancer Patients with Solid Tumors in a Tertiary Care Centre: A Retrospective Study
This study evaluated the prescribing pattern of analgesics in very terminal ill cancer patients who succumbed to their illness in a tertiary care hospital. Methods: This retrospective study was conducted in the Medical R...