Intravenous clonidine for intraoperative hemodynamic stability during laparoscopic surgeries
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 10
Abstract
Clonidine is an alpha 2 adrenoreceptor agonist, which has emerged as an attractive premedication desirable in laparoscopy surgery, wherein significant haemodynamic response is seen. Its effectiveness in providing better intraoperative haemodynamics has been well proven. The minimum safe and effective dose of I.V. Clonidine is not yet determined to attenuate the haemodynamic stress response during laparoscopic surgeries. We did a study in which I.V. Clonidine 2µg/kg was given 30 minutes prior surgery. Haemodynamics variables (heart rate, systolic, diastolic and mean arterial pressure) were recorded at specific timings. Mean arterial pressure above 20% from baseline was considered significant and treated with Inj. Nitroglycerine
Authors and Affiliations
Sudhir W Bhope, Jitendra Waghmare
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