INVESTIGATION OF CHEMICAL AND PHARMACOLOGICAL PROPERTIES OF ESSENTIAL OILS FROM TWO SYZYGIUM SPECIES OF ANDHRA PRADESH, INDIA
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 9
Abstract
Objective: The present investigation is carried out to study the chemical composition, antimicrobial and antioxidant activity of essential oils of two Syzygium species i.e. Syzygium alternifolium (SA) and S. samarangense (SS) leaves.Methods: The essential oils from S. alternifolium (SA) and S. samarangense (SS) leaves were obtained by hydro-distillation and analyzed by GC and GC-MS. The oils were subjected to antimicrobial and antioxidant activities by using in vitro methods.Results: Essential oils (EOs) obtained by hydro distillation were analyzed through GC and GC-MS and resulted 25 compounds from each sample. SA leaf oil was dominated by monoterpene hydrocarbons (53.53%) of which, β-mercene (24.04%), β-pinene (9.23%), β-trans-ocimene (9.2%), cyclofenchene (7.21%) and β-cis-ocimene (2.1%). Whereas SS leaf oil was dominated by sesquiterpene components i.e. viridiflorol (15.05%) α-cubebene (7.71%) and monoterpenes, i.e. β-pinene (11.64%), α-pinene (9.61%) and α-terpineol (5.19%). Both essential oils exhibited strong and broad spectrum of antimicrobial activity. The antimicrobial results showed that SA-leaf oil strongly inhibited Candida rugosa (CR), Bacillus subtilis (BS) and Staphyloccus aureus (ST), whereas SS-leaf oil strongly inhibited CR and Escherichia coli (EC). Among the test organisms, CR was strongly inhibited by both oils by expression of the lowest minimum inhibitory concentrations (MIC). Further, both the test EOs exhibited concentration dependent DPPH scavenging activity indicating the significant antioxidant property.Conclusion: Syzygium alternifolium and S. samarangense leaf essential oils are the good source of natural antimicrobial and antioxidant compounds, which can be used as natural therapeutic agents against human pathogenic organisms.Â
Authors and Affiliations
Prasanna Anjaneya Reddy L, Venkata Ratnam. K, Bhakshu Md Lepakshi, Veeranjaneya Reddy. L, Narasimha Reddy. B
Keywords
Related Articles
- EP ID EP578466
- DOI -
- Views 62
- Downloads 0
INCIDENCE AND RISK FACTORS OF RENAL IMPAIRMENT IN HIV-1 INFECTED PATIENTS RECEIVING TENOFOVIR BASED ANTIRETROVIRAL THERAPY IN A SOUTH INDIAN HOSPITAL
Objective: To identify the incidence and risk factors of tenofovir (TDF) induced nephrotoxicity among People Living with HIV/AIDS (PLHA) receiving TDF-based anti-retroviral therapy (ART) in a South Indian Hospital.Method...
METHOTREXATE FAST DISINTEGRATING TABLET AS A DOSAGE FORM FOR DYSPHAGIA PATIENTS
Objective: The objective of the present study was to develop, optimize and evaluate fast disintegrating tablet (FDT) of methotrexate (MTX) as a dosage form for dysphagia patients with a view to enhance patient compliance...
NOVEL SYNTHESIS OF PROCESS RELATED IMPURITIES OF VALGANCICLOVIR HYDROCHLORIDE
Objective: The present work aimed at synthesis of process related impurities of valganciclovir by using gancyclovir or monobenzyl ganciclovir as starting material comprising the following steps.Methods: Selective hydroly...
TRANSDERMAL PATCHES OF CHITOSAN NANOPARTICLES FOR INSULIN DELIVERY
Objectives: To develop a nanoparticle system with Chitosan for transdermal delivery of insulin.Methods: Chitosan and Tripolyphosphate (TPP) were used to prepare the insulin loaded chitosan nanoparticles based on ionotrop...
ANALGESIC, ANTI-INFLAMMATORY AND ANTIPYRETIC EVALUATIONS OF NEW ISOQUINOLINE DERIVATIVES
Objective: To evaluate the isoquinoline (N-substituted (E)-4-arylidene-isoquinoline-1,3-dione) derivatives (5a-h) for their anti-inflammatory, analgesic and antipyretic activity potentials in animal models using indometh...