Investigation of Hypoglycemic Effect 4-(2--Hydroxyethyl)phenol Compounds Is from Iraqi an Prosopis Juliflora Pods On Level of Glucose Blood of Alloxan - Induced Diabetes Rabbits
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 10, Issue 9
Abstract
Prosopis juliflora is herbal plant traditionally used in different countries to treat diabetes .In present study the chemicals  of Prosopis juliflora pods were specified by GC-MS ,NMR ,IR and TLC techniques which identified the many chemicals family compounds .extraction percentage of 4-(2’-Hydroxyethyl)phenol  compound was    (2.532 % ) . Alloxan –induced diabetic rabbits were prepared in present study after injecting the experimental rabbit with three dose of alloxan  (I.V).Hyperglycemic  rabbits were divided to tow groups. First group was administration orally with 0.3 g/kg of  Phenolic  compound (treatment group)) and second group was administrated orally with normal saline  (control group) . the lowest level of glucose was observed in alloxan –induced diabetic rabbits that administrated with phenolic compound  and the significant decreasing was observed after 4hrs of administration  at ( P<0.001). ). Its can be concluded from the current study the phenolic compound from Prosopis juliflora pods is very good for reduce  glucose blood of hyperglycemic  rabbits the  4-(2’-Hydroxyethyl)phenol compound    isolated  was  purified and identified using TLC ,NMR ,GC-MS,IR techniques.Therefor this compound can be used safely to treat diabetes mellitus.
Authors and Affiliations
Jamal Harbi Hussien Alsaadi, Abbas Dawwas Mattar Al-Maliki
Keywords
Related Articles
- EP ID EP652791
- DOI 10.24297/jac.v10i9.879
- Views 162
- Downloads 0
pH Assist for Highly selective determination of Xipamide by the enhancement of the green emission of Tb3+ optical sensor
The highly selective, accurate method for determination of Xipamide was maintained. The method depends on the enhancement of the green emission band of Tb3+ at 545 nm in the presence of different concentration of  Xipam...
A NOVEL APPROACH OPTIMIZATION RANKED SYMMETRIC SEARCH ENCRYPTION USING CLOUD SECURITY SERVERS
In the track of recent decades there is an especially extensive change in the PC innovation which prompts to an uncountable number of information and data rising in and everywhere throughout the world. Because of this gi...
Exploring Quantitative Structure-Activity Relationships (QSARs) of Non-Tri cyclic Cyclooxygenase-2 (COX-2) Inhibitors by MLR and PC-ANN
Quantitative structure–activity relationship study using principal component artificial neural network (PC-ANN) methodology was conducted to predict the inhibitory activities expressed as pIC50 of 73 non-tri cyclic cyc...
Transesterification of Waste Cooking Oil Catalysed by Crystalline Copper Doped Zinc Oxide Nanocatalyst
Biodiesel has its unique position in the field of renewable energy as alternate fuel to diesel due to fuel price, energy requirement and petroleum crisis. In this study, biodiesel was produced from Waste Cooking Oil (WCO...
Study on sea sand as a partial replacement for fine aggregate
Sand researches around the world are in continuous search for the alternatives of sand. Fine aggregate is an important constituent of concrete and is required in large quantities. Generally, river sand is used as fine ag...