Investigation of the Efficiency and Satisfaction Score of Platelet-Rich Plasma versus Hyaluronic Acid for the Treatment of Knee Osteoarthritis
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Introduction: With the aging population, prevalence of osteoarthritis is continuously on an increase. The management of chondral disease is challenging because of its inherent low healing potential. The aim of this study was to investigate the efficiency and satisfaction of platelet-rich plasma v/s hyaluronic acid for knee osteoarthritis. Materials and Methods: The present study included 115 Patients indicated for the treatment of symptomatic cartilage lesions and/or knee osteoarthritis. The first group of 60 patients was treated using intraarticular application of autologous PRP (PRP group) and 55 patients of the control group (HA group) were treated with HA. After complete medical history and examination, Subjects’ age, gender, height and weight were recorded and their body mass index (BMI) was calculated. Basic routine investigations were done on outpatient basis. Results: The mean age of the study patients was 58±3.4 in PRP group and 62±12.1 in HA Group. There were 36 male and 24 female participants in PRP group and in HA group the male female ratio was 29:26. There were no significant differences between the 2 groups across age, sex, BMI, Vas pain score, or McMaster Universities Osteoarthritis Index. There was a significant difference in the Symptoms duration. Conclusion: PRP demonstrated a statistically significant improvement over HA. Our findings further suggest that both HA and PRP may be a superior treatment for patients with OA.
Authors and Affiliations
Kuldeep Kumar Gogia, Mohd Shahid Bhat
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