INVESTIGATION OF TRIVALENT MACROCYCLIC COMPLEXES AS POTENT BIOLOGICAL ACTIVITY
Journal Title: Indian Journal of Scientific Research - Year 2015, Vol 6, Issue 1
Abstract
Two new Cr(III) macrocyclic complexes have been synthesized bearing the formula M(III)[DPTDH] (BF4)2, M(III)[DCTDH](BF4), Where M=Cr(III), [DPTDH]=(2,6-diacetyl pyridine-N,N’-thiodiacetoyl dihydrazone), [DCTDH] = (2,6-pyridine dicarbonyl dichloride-N,N’-thiodiacetoyl dihydrazone), (BF4) = Tetrafluorobrate. The synthesized complexes were investigated using different physical techniques such as elemental analyses, infra-red, electronic spectra and conductivity measurements. The IR and electronic spectral data in both complexes revel that ligand is coordinated to the central metal ion. The result of analysis shows the complexes to be of octahedral geometry and of electronic nature. The new Macrocyclic complexes have been assessed for antifungal and antibacterial activities against certain microorganism. The complexes have been found to be manifold active biologically then the ligand
Authors and Affiliations
ANUPA , K. DUBEY
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