Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test.
Journal Title: Pharmacological Reports - Year 2013, Vol 65, Issue 4
Abstract
The involvement of glutamate system (particularly the NMDA and AMPA receptors) in the mechanism of antidepressant activity was demonstrated in preclinical and clinical studies.
Authors and Affiliations
Małgorzata Wolak, Agata Siwek, Bernadeta Szewczyk, Ewa Poleszak, Andrzej Pilc, Piotr Popik, Gabriel Nowak
Keywords
Related Articles
- EP ID EP88117
- DOI -
- Views 87
- Downloads 0
The activity of cytochrome P450 CYP2B in rat liver during neuroleptic treatment.
The aim of the present study was to investigate the influence of classic and atypical neuroleptics on the activity of rat CYP2B measured as a rate of 16beta-hydroxylation of testosterone. The reaction was studied in cont...
Impact of ageing on the measurement of endothelium-dependent vasodilation.
Two established methods to assess endothelium-dependent vasodilation in the peripheral circulation have been used in epidemiological research, the invasive forearm technique using intra-brachial infusion of acetylcholine...
How significant is the difference between drug doses influencing the threshold for electroconvulsions?
In this study, three computational methods (log-probit, one-way analysis of variance and linear regression analysis) were applied to statistically determine and compare a minimal dose of the antiepileptic drug--levetirac...
Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats.
Background: The study's aim was to evaluate the anti-inflammatory effect and influence on gastric mucosa after the combined administration of ketoprofen and zinc hydroaspartate (ZHA, 60 mg/kg). Methods: Antiedematous act...
Microparticles are vectors of paradoxical information in vascular cells including the endothelium: role in health and diseases.
Both inflammation and thrombosis can be orchestrated by the interactions between circulating cells, such as leukocytes and platelets, with vascular, endothelial and smooth muscle cells, which, during activation or apopto...