IS CONJUGATED LINOLEIC ACID (CLA) A PROTECTIVE FACTOR IN ATHEROSCLEROSIS? STUDY WITH THE USE OF NEURAL NETWORKS
Journal Title: Pomeranian Journal of Life Sciences - Year 2005, Vol 51, Issue 2
Abstract
Purpose: Conjugated linoleic acid (CLA) is a term used for positional and geometrical isomers of linoleic acid whose two unsaturated bonds are separated by one saturated bond (cis9trans11 and trans10cis12). Cooked meat and milk are among the richest dietary sources of CLA. Recently, much attention has been devoted to CLA due to its anti-cancer, anti-atherogenic, and anti-diabetic properties. Material and methods: Our study group comprised 29 patients aged 45 to 75 years who were operated for atherosclerotic stenosis in the carotid arteries. Results: Venous blood was collected after an overnight fast. Total cholesterol and triglycerides were assayed with enzymatic test kits. HDL-cholesterol was measured after precipitation with sodium magnesium phosphotungstate. LDL-cholesterol was calculated from total cholesterol, triglyceride and HDL-cholesterol concentrations using Friedewald’s formula. A Perkin-Elmer gas chromatograph (model 8500) was used to analyze fatty acids methyl esters. Statistical analysis was performed with the Statistica Neural Networks software. Signifi cantly lower plasma content of c9t11 CLA, linoleic, and arachidonic acids was found in the study group as compared with controls. Parametric analysis disclosed that c9t11 CLA concentrations depended on triglycerides and arachidonic acid in the study group and on linoleic acid and triglycerides in controls. An increase in total cholesterol concentration was associated with a decrease in the concentration of c9t11 CLA in the study group and a parallel increase in the control group.
Authors and Affiliations
EWA STACHOWSKA, IZABELA GUTOWSKA, HALINA SZUMIŁOWICZ, JOANNA BOBER, DARIUSZ CHLUBEK
Keywords
Related Articles
- EP ID EP83622
- DOI -
- Views 59
- Downloads 0
THE POLISH HEALTHCARE SYSTEM: PERSPECTIVES AND POSSIBILITIES FOR ADOPTION OF HEALTHCARE SYSTEMS FROM OTHER COUNTRIES OF THE EUROPEAN UNION
This work was undertaken to describe the basic elements of the Polish healthcare system and to examine possibilities for adoption of solutions existing in healthcare systems of other countries of the European Union. Heal...
Wpływ diety niskowęglowodanowej na stan zdrowia człowieka
Dieta niskowęglowodanowa budzi najwięcej kontrowersji spośród wszystkich modeli żywienia ostatnich lat. Odwraca znaną wszystkim piramidę żywienia, demonizuje stanowiące jej podstawę węglowodany oraz zaleca spożywanie duż...
64-SLICE COMPUTER TOMOGRAPHY FOR DIAGNOSTICS OF THE SMALL BOWEL: COMPUTER TOMOGRAPHY ENTEROCLYSIS
Introduction: Radiologic imaging of the small bowel is the method of choice because other methods are of limited availability. Computer tomography (CT) enteroclysis is the leading modern method for diagnostic imaging of...
EFFECTS OF DIETARY TRANS FATTY ACIDS IN PREGNANCY AND LACTATION
Unsaturated fatty acids with the trans configuration (TFA) are recognized as the most harmful type of fatty acids. The main human source of TFA are foods containing hardened plant oils. Evidence is aplenty that TFA are r...
Nadwrażliwość pokarmowa w populacji dzieci szkolnych w Opolu
Wstęp: Częstość występowania nadwrażliwości na pokarmy u dzieci jest wysoka i wzrasta szczególnie w środowisku miejskim. Celem pracy była ocena częstości występowania objawów nadwrażliwości na pokarmy w populacji dzieci...