IS PSEUDOCHOLINESTERASE RELATED TO LIPID METABOLISM IN CORONARY ARTERY DISEASE?
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 2
Abstract
Background: Pseudocholinesterase is a serum esterase synthesized by liver. The physiological function of Pseudocholinesterase is not known. It has been proposed that it plays a role in lipid metabolism. Altered lipid metabolism is found in coronary artery disease. Aims and Objectives: To evaluate the association of serum pseudocholinesterase activity with lipid profile in coronary artery disease. Materials and Methods: This cross sectional study comprised 60 subjects, which included equal number of healthy volunteers and myocardial infarction cases. Serum pseudocholinesterase activity and lipid profile was estimated. The data was statistically analyzed. Results: The serum pseudocholinesterase activity, cholesterol, triglycerides and low density lipoprotein were increased in myocardial infarction patients. Serum pseudocholinesterase correlated with the lipid parameters in cases. Conclusion: Increased pseudocholinesterase activity may alter lipid metabolism in coronary artery disease.
Authors and Affiliations
Girish M. Desai*| Department of Biochemistry, Mahadevappa Rampure Medical College, Gulbarga, Karnataka, India, Raghunandana R| Department of Biochemistry, Siddhartha Medical College, Tumkur, Karnataka, India, Shreeshail Ghooli| Assistant Professor in Department of Community Medicine at Mahadevappa Rampure Medical College, Gulbarga, Karnataka, India, Netravati Sajjan| Department of Biochemistry, Mahadevappa Rampure Medical College, Gulbarga, Karnataka, India
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