ISOLATION, PARTIAL CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF A FLAVONOL FROM SUDANESE INDIGOFERA OBLONGIFOLIA (FABACEAE)
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2018, Vol 4, Issue 10
Abstract
Various Indogifera species have been investigated. Indigofera oblongifolia possesses, beside others, hepatoprotective, antimicrobial and lipoxygenase inhibition properties. In this study the heartwood of Indigofera oblongifolia was extracted with ethanol and the extract was purified by paper chromatography which gave a pure flavonol. The structure of this flavonoid was partially elucidated via some spectral tools (UV and 1HNMR). The antimicrobial activity of the isolated flavonol was assessed via cup plate agar diffusion bioassay. Compound I showed good activity against Escherichia coli, Pseudomonas aeroginosa and Bacillus subtillus. It also showed weak activity against Aspergillus niger and weak anticandidal potency. The compound also exhibited partial activity against Staphylococcus aureus. The antioxidant properties of compound I has been studied and excellent free radical scavenging capacity has been detected.
Authors and Affiliations
Prof. Abdel Karim M.
Keywords
Related Articles
- EP ID EP656369
- DOI -
- Views 164
- Downloads 0
ALLIUM PORRUM: A REVIEW
Plants with medicinal capacity have always been an important target for drug development. Plants of the genus Allium have recognised as rich sources of secondary metabolites endowed with interesting biological activities...
CONCEPTUAL STUDY OF LANGHANA AS TREATMENT IN AMAVASTHA OF VYADHIS
Ayurveda is an ancient science of life, i.e. the word “Ayurveda” itself says “Ayusho vedaha” that means veda of life is Ayurveda. This life science is very ancient estimated about 5000 years ago. Ayurveda blessed us with...
A COMPARATIVE STUDY OF PADMADI LAUHA AND IRON FOLIC ACID IN MANAGEMENT OF GARBHINI PANDU
Aim: To evaluate the efficacy of padmakadi lauha in cases of Garbhini pandu.Introduction: Pandu means pallor of body which can be correlated with 'Anaemia' of modern science. Bala varna hani of Garbhini in 6th month of p...
CORONARY ARTERY EVALUATION BY APPLICATION OF CARDIAC CT
Cardiovascular disease is the leading cause of death worldwide,[1] Several factors responsible for the increasing percentage of cardiovascular diseases, including a tobacco use, longer average life span, decreased physic...
TYPE II DIABETES MELLITUS AND DIASTOLIC DYSFUNCTION; 100 CASES
Objective; Frequency of diastolic dysfunction in patients having type II DM Methodology; This was a cross sectional study that was conducted at Medical department of Sheikh Zayed Hospital, Rahim Yar Khan during May to Oc...