Joint Effects of Alcohol Consumption and Cigarette Smoking on Atherogenic Lipid Profile: In Men at Durg (Chhattisgarh)
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Purpose: The present study examines the Joint effects of alcohol consumption and cigarette smoking on atherogenic lipid profile among male adults in Durg. Methods: A total number of 490 male subjects were selected at CCM Medical college Hospital Durg. 297 males are alcohol takers and chronic smokers, who were smoke more than 10-15 cigarettes / bidi per day and take more than 180 ml alcohol in the form of whiskey, rum or bear more than 3 times per week from last 5 years with an average range of 37 to 50 years. 193 nonalcoholic and non-smokers age matched males were selected for control group. Controls were clinically and physically normal and healthy. Results: The frequency of consumption of alcohol was; daily 166 patients (55.89 %), 3-5 times per week in 131 patients (44.10 %) and all patients 297 (100%) smokes 10-15 cigarettes or bidi per day. Majority alcohol dependent patients drink alcohol alone and some are claimed to drink only in company or with friends. In the observed population, the value of TC, TG in cigarette / bidi smokers increased significantly and monotonically with increased level of cigarette smoking and alcohol consumption. In addition alcohol intake significantly associated with increased HDL-cholesterol and decreased LDL level in a dose dependent manner. The effect of alcohol consumption on HDL-c and TG levels was substantially greater for heavy smokers than light smokers, while alcohol intake exerted a strong positive influence on HDL-c level regardless of level of cigarette / bidi smoking. Conclusion: On the basis of our study results we concluded that the lipid profile changes in patients of alcohol drinkers and cigarette smokers, with some correlation to the liver dysfunction. Alcohol causes alteration in lipid profile level in blood including those which predispose to CHD. Cigarette smoking and alcohol consumption were confirmed to have similar effect on lipid and lipoproteins as in Caucasians. A significance of joint exposure to drinking and smoking predict lipid levels were evident. Low or moderate drinking alcohol over prolonged periods has been linked to have protective influence for development of CHD, through increase in HDL-c levels.
Authors and Affiliations
N. S. Dixit, Suvimal Dutta, Karan Singh Chandrakar
Keywords
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- EP ID EP547825
- DOI 10.21276/ijmrp.2017.3.3.033
- Views 52
- Downloads 0
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