Kaposi Sarcoma Still A Problem in Our Hiv Infected Persons: A Site Experience
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Over 70 million people have been infected by the Human Immunodeficiency virus(HIV) worldwide and the Sub-Saharan Africa has the largest population of people living with Human immunodeficiency virus/Acquired immune disease (HIV/AIDS). Nigeria had about 3.3million people living with the disease as at 2015.(1) There is increase risk of AIDS defining and non AIDs defining cancer in infected persons(2) Despite Antiretroviral drugs, Kaposi sarcoma is still common among HIV infected patients in our setting and runs a very aggressive course. We analyzed the spectrum of malignancies among our HIV infected patients to find out how frequent KS is among these patients. This is a prospective data collection of HIV infected patients at two major treatment facilities in Plateau state over a three year period January 2013 to January 2016.A total of 343 participants were enrolled, 184(56.4%) were males and 159(46.4%) were females. Majority of reponndants 100(29.1%) were in the age group 37 - 47years, 286(86.4%) married and 244(31.1%) were unemployed. Commonest malignancy found was Kaposi sarcoma(KS) 129(37.6%). Most of the participants 197(57.43%) were on first line drug regiment while 146(42.57%) were on second line. Of those found to have KS, 69(53.49%), CI: 44.50%-62.31% of them were on first line drug regiment while 60(46.51%) , CI: 37.69%- 55.50% were on second line.Kaposi sarcoma is still a major problem among our HIV infected patients and is a significant factor for increased mortality. There is need for structured surveillance system incorporated into our HIV treatment programs.
Authors and Affiliations
Isichei M. W, A . F. Ale, Peter S D, Shilong D J, Misauno A. M
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