Ketamine: from narcotic analgesics to antidepressants
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 8
Abstract
Ketamine compound was firstly synthesized for more than 60 years. It is widely used in clinical anesthesia due to its potent analgesic effect and lower deleterious impacts on circulatory and respiratory functions. Very recently, its rapid and long-lasting antidepressant effect attracted increasing attentions in the topic field. We therefore reviewed the pharmacological properties of ketamine, its clinical application as a narcotic analgesic, and antidepressant effect of its metabolites.
Authors and Affiliations
JIANG Chenqi*, XU Xiangqing, XIE Li, LIU Cunming, YANG Chun（*Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China）
Keywords
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- EP ID EP743084
- DOI 10.13429/j.cnki.cjcr.2024.08.001
- Views 9
- Downloads 0
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