Ketamine- Propofol or Fentanyl- Propofol intravenous infusion a better combination for short surgical procedures in paediatric patients, a comparative study
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3
Abstract
Introduction Paediatric patients usually present with various painful conditions that require immediate surgical interventions Many studies have been done on ketamine propofol combination to prove its efficacyAim The aim was to compare the effect of propofolketamine and propofolfentanyl infusion in terms of haemodynamic stability postoperative sedation postoperative nausea and vomiting and adverse effects if anyMaterials and Methods This was a prospective randomized double blind controlled trial conducted in 60 patients of ASA Grade I II of age group 3 to 14 years Patients were randomly allocated into two groups to receive either ketamine 1mgkg before induction group PK n30 or fentanyl 15 ug kg before induction group PF n30 and patients in both groups were induced with propofol 2 mg kg and maintained on propofol infusion at rate of 50 ug kg min Heart rate and blood pressure were monitored throughout the procedure Sedation was monitored by Ramsay sedation score and side effects were notedResults In PF group there was a fall in heart rate as compared to PK group There was a statistically significant fall in systolic blood pressure SBP diastolic blood pressure DBP and mean arterial pressure MAP in PF group P 005 In PK group there is no significant fall in SBP DBP and MAP The patients in group PF were more sedated postoperatively and there was increased incidence of postoperative nausea and vomiting in group PF as compared to group PKConclusion Propofolketamine combination is better as compared to propofolfentanyl in terms of haemodynamic stability and better recovery with less side effectsKeywords Propofol Ketamine Fentanyl Paediatric procedures
Authors and Affiliations
Shital Mahendra Kuttarmare, Anandkumar Pande
Keywords
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- EP ID EP476497
- DOI 10.18231/2394-4994.2018.0072
- Views 67
- Downloads 0
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