KOttner's tumor (chronic sclerosing sialadenitis) — a rare cause of submandibular gland enlargement
Journal Title: Otolaryngologia Polska - Year 2011, Vol 65, Issue 4
Abstract
SUMMARY KOttner's tumor is a benign tumour-like lesion of the salivary glands. Pre-dominantly affects the submandibular gland. It is also known as chronic sclerosing sialoadenitis or cirrhosis of submandibular gland. This is an underrecognized entity in the surgical pathology and cytology literature. Most patients experience recurrent pain, discharge and swelling that is often associated with eating, but others only have asymptomatic hard swelling of the submandibular gland. Histologic examination of the excised submandibular glands revealed preserved lobular architecture, thickening of interlobular septa by sclerotic tissue, dense Iymphoplasmacytic infiltrate, preservation of ducts with periductal fibrosis, and variable Ioss of acini. The morphologic appearance, in conjunction with the elevated IgG4 expres-sion, distinguishes chronic sclerosing sialadenitis from other inflammatory diseases of the salivary glands. Chronic sclerosing sialadenitis belongs to the spectrum of IgG4-related diseases. We present a case of KOttner's tumor in a 62-year-old female treated by surgery. Although this disease was first described by KOttner in 1896, this clinical entity which masquerades as carcinoma is underdiagnosed by many surgeons. There is not enough evidence to support any diagnostic means that could help in the differential diagnosis of this benign condition. Given the high rate of malignancy in firm, painless Iesions of the submandibular gland, surgical excision is often advocated and KOttner's tumor is usually diagnosed by the histopathologist.
Authors and Affiliations
Jarosław Markowski, Tatiana Gierek, Małgorzata Witkowska, Monika Świderek, Ewa Zielińska-Pająk, Jacek Pająk, Lucyna Klimczak-Gołąb, Katarzyna Smółka
Keywords
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