Kserostomia jako powikłanie radioterapii: mechanizm, diagnostyka, profilaktyka i leczenie – aktualny stan wiedzy
Journal Title: Otolaryngologia Polska - Year 2014, Vol 68, Issue 1
Abstract
Definition and prevalence of xerostomia were shortly presented. Radiosensitivity of the salivary glands, mechanism, diagnostics, and possible prediction methods of the intensity of xerostomia in the pre-radiotherapy period are widely discussed. Prevention of xerostomia: salivary gland sparing radiotherapy, cytoprotective agents, preservation by stimulation with cholinergic muscarinic agonists, surgical transfer of submandibular glands according to ASCO Management Guidelines and Quality of Life Recommendations were cited. Oral Care Study Group (2010) therapeutic approaches for relieving xerostomia are referred. Current therapies, restricted to symptom relief such as oral hygiene with fluoride agents, antimicrobials to prevent dental caries, saliva substitutes to relieve symptoms, and sialogenic agents to stimulate saliva were also discussed.
Authors and Affiliations
Jarosław Kałużny, Małgorzata Wierzbicka, Hanna Nogala, Piotr Milecki, Tomasz Kopeć
Keywords
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