“LACTATE DEHYDROGENASE AS A MARKER ENZYME TO DETECT SILICAEXPOSURE INDUCED CYTO-TOXICITY IN AGATE WORKERS”
Journal Title: INTERNATIONAL JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH - Year 2014, Vol 2, Issue 6
Abstract
Agate-workers in Khambhat region of Gujarat (India) are chronically exposed to the silica-dust due to agate grinding, and made them susceptible for silicosis. Due to lack of proper diagnosis at early stage, the workers continue to be exposed with silica-dust until the prognosis of silicosis. The present study was undertaken to investigate total lactate de-hydrogenase (LDH) activity in blood samples of silica-exposed agate workers as a less invasive way to measure for silica-induced toxicity.
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