Langerhans Cell Histiocytosis: Rare Disease Treated With Chemotherapy and Radiotherapy
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Langerhans Cell Histiocytosisrepresents a rare benign disorder previously designated as Histiocytosis X Varity” Type II Histiocytosis or Langerhans cell Granulomatosis, it occurs when the body accumulates too many immature langerhans cell a subset of the larger family of cell known as histocytes. Langerhans cell are of white blood cell that normally help the body to fight against infection. Langerhans cell histocytosis is most commonly characterized by single on multiple osteolytic bone lesion but also ulcerations of skin & soft tissue and also involvement of the CNS. Bones are the most common localization of disease (40- 78%). Surgery is the treatment of choice in limited form of histiocytosis but in diffuse form only chemotherapy is used. The most of researches also recommends the radiotherapy in conditions, like Recurrence or progression of disease bone pain , exopthalmus, non surgical local changes. The aim of this study is to present four such rare patients having multi system diseases with multiple organs system treated with chemotherapy & radiotherapy at our institution.
Authors and Affiliations
Dr. Manjula Beck, Dr. V B Rathore, Prof V. Choudhary, Prof S. K. Azad, Dr. P. Chandrakar, Dr. Rajeev R Jain, Dr. Madhu Verma, Dr. Devvrat Hisikar, Dr. Rajendra Patel, Dr. R M Chandola, Mr S. K. Patnaikuni, Mr Ajay Taide
Keywords
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- EP ID EP597279
- DOI 10.9790/0853-1605044041.
- Views 83
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