Leiomyosarcoma of the Tongue - A Case Report
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2013, Vol 15, Issue 1
Abstract
Soft tissue sarcomas arising in the head and neck are rare among adults. They account for approximately 10% of all soft tissue sarcomas and approximately 1% of head and neck tumors. Leiomyosarcomas are among the unusual soft tissue sarcomas in the head and neck which account about 0.2% of the cases in the reported series. We are presenting a case of 30-year-old man with leiomyosarcoma of the lateral aspect and base of oral tongue, who was operated outside in private hospital followed by postoperative radiation therapy at Gujarat Cancer Research Institute, Ahmedabad. Initially he presented with ulcer over left lateral aspect of tongue since two months and fine needle aspiration cytology was reported as squamous malignant cells. Preoperative computed tomography (CT) scan revealed 46x25x53 mm well defined lesion in oral cavity on left side of tongue extending up to floor of mouth with few enlarged nodes seen at level II on left side of neck, largest node measuring approximately 17x12 mm. Patient underwent wide excision of the lesion on left lateral side and base of tongue along with left modified neck dissection type II. Gross examination of operated specimen (tumor size) was 5x4.5x2.5 cm; while microscopically tumor showed malignant spindle cell neoplasm and neoplastic cells expressed vimentin and smooth muscle actin. Patient was treated with radiation therapy with linear accelerator (6 megavoltage photons) with two lateral opposed portals using orfit for immobilisation for total dose of 60 Gy (200 cGy/# , five days a week x 30 days). During treatment patient had developed grade II mucositis, grade I dermatitis and grade II dysphagia, which were manageable. There was no evidence of disease at the end of 4 months of follow up. Appropriate treatment options, and accurate estimation of survival outcome, however, will not be conclusive until sufficient cases have been reviewed.
Authors and Affiliations
Jayvir Patel, Jayprakash Neema, Rakesh Vyas, Dhaval Jetly
Keywords
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