Lesinurad: A novel drug for the treatment of hyperuricemia associated with Gout in combination with a Xanthine Oxidase Inhibitor
Journal Title: JOURNAL OF MEDICAL COLLEGE CHANDIGARH - Year 2018, Vol 8, Issue 1
Abstract
Lesinurad is a selective inhibitor of URAT 1(Uric acid absorption inhibitor) and doesn’t inhibit organic anion transporters (e.g. OAT1 & 3) which make it to be an effective uricosuric agent with minimal clinically significant drug interactions, unlike probenecid. Lesinurad has been approved by USFDA ((United States Food and Drug Administration) on December 22nd , 2015, for the patients with gout, who didn’t achieve normal blood uric acid levels with xanthine oxidase inhibitor alone.
Authors and Affiliations
Sangeeta Bhanwra, Kaza Ahluwalia
Keywords
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