Leucine: green and efficient catalyst for the synthesis of 4H-chromenes
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 10, Issue 9
Abstract
Leucine, a naturally occurring α-amino acid, has been found as an effective catalyst to effect the one-pot three-component condensation reaction between aromatic aldehydes, malononitrile and 5,5-dimethyl-1,3-cyclohexanedione (dimedone). Various 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile derivatives are conveniently prepared by these reactions in excellent yields. High yields, short reaction times, simple work-up, use of green and naturally occurring catalyst and solvent are the main merits of the present protocol.
Authors and Affiliations
Davood Azarifar, Younes Abbasi, Omolbanin Badalkhani
Keywords
Related Articles
- EP ID EP652795
- DOI 10.24297/jac.v10i9.6168
- Views 168
- Downloads 0
Oxidative Study of Benzaldehyde by Isoqauinolinium Bromo Chromate
The kinetics analysis of the oxidative reaction between benzaldehyde and oxidant is quinolinium Bromo chromate was reported in aqueous 40% acetic acid medium at 313 K. The rate of reaction varies first-power of [IQBC] an...
AN EFFICIENT SYNTHESIS OF GEM-DIHYDROPEROXIDES AND 1,2,4,5-TETRAOXANES CATALYZED BYCHLOROSULFONIC ACIDAS A NEW CATALYST
Chlorosulfonic acid was used as an active, low-cost and reusable solid catalyst for conversion of ketones and aldehydes to corresponding gem-dihydroperoxides using 30% aqueous hydrogen peroxide at room temperature. The r...
X-ray Structure Refinement and Vibrational Spectroscopy of Ca8Gd2 (PO4)6 O2
The present paper is interested in the study of compounds from the apatite family with the general formula Ca10 (PO4)6A2. It particularly brings to light the exploitation of the distinctive stereochemistries of two Ca po...
Electrocatalytic Oxidation of Nitric Oxide at Carbon Paste Electrode Modified with Chromium (III) Oxide
Chromium (III) oxide was used as a bulk mediator in carbon paste electrodes to improve the better performance of the carbon electrodes for the detection of nitric oxide in comparison with unmodified electrodes. The react...
Nanocrystalline Hydroxyapatite Ceramics Prepared by Hydrolysis in Polyol Medium, Microstructure and Mechanical Properties after Spark Plasma Sintering
This Letter describes a new approach for the synthesis of hydroxyapatite (HA) nanoparticles by polyol process has been successfully conducted by spark plasma sintering process, resulting in a dense hydroxyapatite compact...